This section needs expansion with: add major highlights for college career including all-american awards, team championships, MVPs. You can help by adding to it. (September 2022)
Professional career
New York Red Bulls II
On 11 January 2022, Nikopolidis was drafted by the New York Red Bulls II with the 71st pick in the 2022 MLS SuperDraft. [1] Nikopolidis, officially signed his first contract with the club on 2 March.[2] Nikopolidis made his professional debut on 2 April 2022, during a 3–2 loss to FC Tulsa.[3] Nikopolidis earned his first professional shutout on 15 July 2022, during a 1–0 win over Indy Eleven.[4]