The fourth cabinet of Ion C. Brătianu ruled Romania from 9 June 1881 to 20 March 1888.

The ministers of the cabinet were as follows:^[1]

• President of the Council of Ministers:

• Ion C. Brătianu (9 June 1881 - 20 March 1888)

• Minister of the Interior:

• Constantin A. Rosetti (9 June 1881 - 25 January 1882)
• Ion C. Brătianu (25 January - 1 August 1882)
• Gheorghe Chițu (1 August 1882 - 23 June 1884)
• Ion C. Brătianu (23 June 1884 - 29 April 1887)
• Gen. Radu Mihai (29 April 1887 - 1 March 1888)
• (interim) Constantin Nacu (1 - 20 March 1888)

• Minister of Foreign Affairs:

• Eugeniu Stătescu (9 June 1881 - 1 August 1882)
• Dimitrie A. Sturdza (1 August 1882 - 2 February 1885)
• Ion Câmpineanu (2 February - 28 October 1885)
• (interim) Ion C. Brătianu (28 October - 16 December 1885)
• Mihail Pherekyde (16 December 1885 - 20 March 1888)

• Minister of Finance:

• Ion C. Brătianu (9 June - 1 December 1881)
• Gheorghe Chițu (1 December 1881 - 25 January 1882)
• George Lecca (25 January 1882 - 13 September 1885)
• (interim) Constantin Nacu (13 September - 16 December 1885)
• Constantin Nacu (16 December 1885 - 1 March 1888)
• Dimitrie A. Sturdza (1 - 20 March 1888)

• Minister of Justice:

• Mihail Pherekyde (9 June - 16 November 1881)
• (interim) Eugeniu Stătescu (16 November 1881 - 25 January 1882)
• Gheorghe Chițu (25 January - 1 August 1882)
• Eugeniu Stătescu (1 August 1882 - 30 September 1883)
• (interim) Gheorghe Chițu (30 September - 15 November 1883)
• Nicolae Voinov (15 November 1883 - 14 January 1885)
• (interim) Ion Câmpineanu (14 January - 2 February 1885)
• Constantin Nacu (2 February - 16 December 1885)
• Eugeniu Stătescu (16 December 1885 - 1 March 1888)
• Dimitrie Gianni (1 - 20 March 1888)

• Minister of War:

• (interim) Ion C. Brătianu (9 June - 1 December 1881)
• Ion C. Brătianu (1 December 1881 - 25 January 1882)
• Gen. Gheorghe Angelescu (25 January - 1 August 1882)
• Ion C. Brătianu (1 August 1882 - 23 June 1884)
• Gen. Ștefan Fălcoianu (23 June 1884 - 13 January 1886)
• (interim) Ion C. Brătianu (13 January - 21 February 1886)
• Gen. Alexandru Anghelescu (21 February 1886 - 5 November 1887)
• (interim) Ion C. Brătianu (5 November 1887 - 20 March 1888)

• Minister of Religious Affairs and Public Instruction:

• Vasile Alexandrescu Urechia (9 June 1881 - 1 August 1882)
• Petre S. Aurelian (1 August 1882 - 23 June 1884)
• Gheorghe Chițu (23 June 1884 - 2 February 1885)
• Dimitrie A. Sturdza (2 February 1885 - 1 March 1888)
• Constantin Nacu (1 - 20 March 1888)

• Minister of Public Works:

• Gen. Nicolae Dabija (9 June 1881 - 1 August 1884)
• (interim) Dimitrie A. Sturdza (1 August 1884 - 2 February 1885)
• Gen. Radu Mihai (2 February 1885 - 29 April 1887)
• Petre S. Aurelian (29 April 1887 - 20 March 1888)

• Minister of Agriculture, Trade, Industry and Commerce:^[2]

• Ion Câmpineanu (1 April 1883 - 2 February 1885)
• Anastase Stolojan (2 February 1885 - 17 October 1886)
• (interim) Ion C. Brătianu (17 October 1886 - 29 April 1887)
• Vasile Gheorghian (29 April 1887 - 1 March 1888)
• Nicolae Gane (1 - 20 March 1888)