Unlike its original broadcast, Netflix released the series with a total of 90 episodes,[5] and with a totally different ending to the one broadcast by Telemundo. Thus leaving an open ending to produce a new season, a fact that Telemundo did not confirm.[6]
Plot
Two years later, Catalina, la grande (Carmen Villalobos) assumes her new duties and responsibilities as the new director of the DEA in Colombia, her daughter Mariana (Stephania Duque), El Titi (Gregorio Pernía) and Dayana (Elianis Garrido) they have associated with Yésica Beltrán (Kimberly Reyes), their worst enemy, whose ambitions are increasingly dangerous. This time it was devastating to return with a formidable weapon since La Diabla has a new face thanks to a total face transplant. This finally manages to infiltrate the organization of the DEA precisely with the help of Mano Negra (Juan Pablo Gamboa). Without knowing it, Catalina Santana works hand-in-hand with Yésica but who presents herself under a new identity, that of Valeria Montes with the aim of slowly destroying her to end the growing rivalry that has existed between them for three decades.
Meanwhile, Catalina, la grande will have to fight against the world of drug trafficking and a new cartel of criminals who threaten to flood the country with a new synthetic drug that will trigger a war between good and evil that will put Catalina's world to the test and of all those around her, like her friends Paola (Alejandra Pinzón) and Vanessa (Estefanía Gómez), recruited from the DEA. In addition, Catalina, la grande will be cornered by Zoraya Fuentes (Eileen Roca), who became Ingrid Román regarding her husband Santiago (Roberto Manrique), who is unjustly in jail because of Zoraya.
On the other hand, calm finally comes to Catalina, la mediana (Carolina Gaitán) and Hernán Darío (Juan Pablo Urrego) after losing their child.
A restaurant serves as a laboratory for manufacturing drugs. Catalina, director of the DEA in Colombia, cannot believe that her daughter is a member of the Babys cartel.
Mano Negra offers Yésica the cure to save her from her illness. In return, she must fulfill six important missions. In the first task the other Babys will participate.
Valeria fools her boss and leaves the country. The Babys cartel embarks on the trip to Las Vegas, but first Mariana calls her mother. Catalina must hurry to recover her daughter.
Mariana demonstrates her qualities and is willing to do everything in order to consolidate herself in drug trafficking. She knows that her mother is chasing her and is ready to face her.
Mano Negra negotiates with the gangsters the sale of the dangerous XY4 drug for 200 million dollars. Catalina knows the place of this meeting and arrives accompanied by her trusted agent.
Mano Negra and everyone in the meeting shoot mercilessly towards the pipeline. They know that there is at least one hidden agent. Catalina falls and when she opens her eyes, Mariana decides her future.
The gangsters bid with exorbitant sums for the XY4 drug. In the middle of their encounter they receive a hard blow. Catalina suffers and asks her daughter to kill her. Mariana activates the trigger.
Catalina receives an unexpected call from Titi. She knows that she must make a decision soon if she wants to recover her daughter and save the life of agent Valeria.
Catalina's decision jeopardizes the operation of the DEA. Titi's life is also at stake. Albeiro, in the midst of his sadness, communicates with Catalina to give her bad news.
Catalina escapes from her colleagues and goes alone to meet Titi. She arrives at the hotel room, handcuffed and blindfolded; He waits for her and is ready to fulfill his mission.
The day of the exchange arrives. Catalina asks that Valeria and Mariana be released. At that moment, Titi is shot, a shootout breaks out and Catalina panics for her daughter.
Titi can do nothing to save his love. Soon, his partners are going to rescue Mariana and Catalina. Mano Negra wants Catalina Santana's head on his desk.
La Diabla fools everyone and takes advantage of the carelessness of the nurse to communicate with Mano Negra and tell him her plan. Catalina is cornered and has no choice but to shoot to kill.
Dr. Lugo injects Santiago, Jota and his group with the medicine to revive them. But despite his attempt, he is worried because they do not react and are transferred to the morgue.
The DEA team returns to Colombia. Natalia sees Valeria hiding in the bathroom, senses that something is wrong and decides to enter to face her. La Diabla reacts with all her energy.
Albeiro goes to his appointment with Yésica and does not know how to escape. She requires him to fulfill an impossible mission in exchange for receiving HIV vaccines.
La Diabla forces Albeiro to something more than a kiss. He fulfills his next task, which hits Hilda deeply. Salvatore doesn't know what to do with the woman he loves.
The car bomb explodes at the doors of the anti-drug event. The surprise is greater when Julia presents herself with a bouquet of flowers and a bloody message. Catalina suffers and Mano Negra celebrates.
Mariana tells La Diabla some things, including a secret from Titi that can lead to his death. Now he is in danger. A new prisoner falls into the clutches of Valeria.
Yésica calls Mano Negra and accuses Titi of warning Catalina of the attack. Everyone in the group points to him, but Titi takes out two grenades. It seems there is no escape.
Catalina already knows that the dead revive. The cartels do not slow down and move their pieces to dominate the XY4 market. Mano Negra does not trust Dayana and he makes it clear to her.
Albeiro calls Catalina and will show her that Yésica is alive. They agree to meet in the Pereira viaduct. She confirms that she will go because she also has a lot to tell him.
Black Hand is desperate not to have the formula of the XY4 drug, he loses his head and wants to kill. His partner, La Diabla decides to end Morón and Cardonita.
The Titi enjoys his supposed death. Dayana pretends to be Mariana's great friend, advises her not to go to Titi's funeral, but Mariana is enraged and faces her to death.
Catalina wants to see with her own eyes the body of Titi. With pain, she approaches the coffin and is shocked. There she discovers that someone very close to Titi is present at the funeral.
Leticia arrives at the Berrío event, she says the candidate's partner is Carla, her missing daughter. From the car, Lucrecia watches Leticia and follows her to talk to her.
Mano Negra finalizes the details with Santos, to end the candidate Berrío, who every day passes, is more in love with the agent Valeria. Lucrecia is urged to speak with Catalina.
The great moment of the presidential debate arrives. Nobody knows what to do when seeing Berrío lose control, his only idea is to kill Conde, his electoral opponent. Valeria savors the situation.
Valeria must act quickly. The DEA suspects that there is an infiltrate in the organization that placed something in the drink of candidate Alfonso Berrío. Catalina makes a firm decision.
Albeiro is against the ropes because he doesn't want to hit Jota. Yésica threatens him with killing Hilda, if he decides not to end his great friend. The two fighters know that their life is at stake.
Mano Negra wants to delight in seeing people suffer. It is not enough to see the fights, he wants something more dark. To achieve his plan he already has in mind the ideal candidate.
La Demonia has La Diabla cornered, who does not know how to act. Agent Valeria looks for her best weapon to escape from this situation and plan her next steps.
La Cuina does not see Titi with good eyes, faces him and puts him to the test. El Titi must decide whether to take or reject the proposals of his partner.
Candidate Berrío knows that his life is in danger. After thinking about it, he makes a key call to his beloved girlfriend to meet as soon as possible. Valeria agrees to meet him.
Calvo is on his way to fulfilling his mission of killing his own son. The thug of La Dibla is sunk and shares secrets with Albeiro. Meanwhile, Valeria is surprised with what she hears.
Mariana is desperate and wants to flee Mexico as soon as possible. She knows that her brother and daughter are in danger. Mano Negra is thirsty for revenge.
