Following her graduation, Wike successfully enrolled in Law School. She achieved the Barrister-at-Law degree (B.L.) in 1997. A year later, she was admitted to the Nigerian bar, eventually commencing practice in Port Harcourt, Rivers State.
Wike joined Efe Chambers as Legal Counsel in charge of litigation. She was later selected to serve as Magistrate Grade I. While in the service, she rose to Chief Magistrate Grade II, and from there became High Court judge in February 2012.[2]