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Within the European Union (EU), Directorates-General are departments with specific zones of responsibility. Within the European Commission specifically, Directorates-General are the equivalent of national-level ministries. Most are headed by a European Commissioner, responsible for the general direction of the Directorate-General, and in charge of (politically responsible for) the corresponding policy area; and a director-general, responsible for the management of day-to-day affairs, who reports to the European Commissioner.

Nearly all of the top-level organisational divisions of the Secretariat of the European Parliament and the General Secretariat of the Council of the European Union are also termed Directorates-General.

The European Patent Office (part of the European Patent Organisation, separate from the EU) also has Directorates-General, which are administrative groupings of departments.

The Directorates-General of the European Commission are divided into four groups: Policy DGs, External relations DGs, General Service DGs and Internal Service DGs. Internally, the DGs are referred to by their abbreviations, provided below.

In addition to its Legal Service, the Secretariat of the European Parliament is composed of several Directorates-General, each of which has an official abbreviation.^[2][3][4]

The General Secretariat of the Council of the European Union is composed of several Directorates-General, which are each headed by a respective director-general or deputy director-general.^[5][6]

• List of European Commission committees by Directorates-General
• European Civil Service
• Joint Research Centre (European Commission)
• Permanent Secretary
• Council of the European Union