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CSPG5
Identifiers
Aliases	CSPG5, NGC, chondroitin sulfate proteoglycan 5
External IDs	OMIM: 606775; MGI: 1352747; HomoloGene: 4795; GeneCards: CSPG5; OMA:CSPG5 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	47,580,792 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	110,091,644 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; retinal pigment epithelium; ; frontal pole; ; Brodmann area 23; ; Epithelium of choroid plexus; ; Brodmann area 10; ; Region I of hippocampus proper; ; orbitofrontal cortex; ; entorhinal cortex; ; Brodmann area 46;
	Top expressed in
	visual cortex; ; primary visual cortex; ; dentate gyrus of hippocampal formation granule cell; ; superior frontal gyrus; ; cingulate gyrus; ; prefrontal cortex; ; nucleus of stria terminalis; ; primary motor cortex; ; anterior amygdaloid area; ; piriform cortex;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; growth factor activity;
Cellular component	integral component of membrane; Golgi apparatus; endoplasmic reticulum membrane; membrane; Golgi membrane; plasma membrane; integral component of plasma membrane; extracellular region; cell surface; lysosomal lumen; endoplasmic reticulum; Golgi lumen; Golgi-associated vesicle membrane; glutamatergic synapse; GABA-ergic synapse; integral component of postsynaptic membrane;
Biological process	cell differentiation; chondroitin sulfate biosynthetic process; modulation of chemical synaptic transmission; intracellular transport; nervous system development; multicellular organism development; chondroitin sulfate catabolic process; regulation of growth; dermatan sulfate biosynthetic process; regulation of signaling receptor activity; trans-synaptic signaling, modulating synaptic transmission; regulation of synaptic vesicle exocytosis; cytoskeleton organization; glial cell projection elongation; positive regulation of substrate adhesion-dependent cell spreading; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	10675
	29873
	ENSG00000114646
	ENSMUSG00000032482
	O95196
	Q71M36
	NM_006574; NM_001206942; NM_001206943; NM_001206944; NM_001206945
	NM_001166273; NM_013884
	NP_001193871; NP_001193872; NP_001193873; NP_001193874; NP_006565
	NP_001159745; NP_038912
	Wikidata
View/Edit Human	View/Edit Mouse

Chondroitin sulfate proteoglycan 5 is a protein that in humans is encoded by the CSPG5 gene.^[5]^[6]

Interactions

CSPG5 has been shown to interact with GOPC.^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000114646 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000032482 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Yasuda Y, Tokita Y, Aono S, Matsui F, Ono T, Sonta S, Watanabe E, Nakanishi Y, Oohira A (May 1999). "Cloning and chromosomal mapping of the human gene of neuroglycan C (NGC), a neural transmembrane chondroitin sulfate proteoglycan with an EGF module". Neurosci Res. 32 (4): 313–22. doi:10.1016/S0168-0102(98)00098-4. PMID 9950058. S2CID 39609929.
^ "Entrez Gene: CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C)".
^ Hassel, Burkhard; Schreff Matthias; Stube Eva-Maria; Blaich Uta; Schumacher Stefan (Oct 2003). "CALEB/NGC interacts with the Golgi-associated protein PIST". J. Biol. Chem. 278 (41). United States: 40136–43. doi:10.1074/jbc.M305577200. ISSN 0021-9258. PMID 12885772.