Somerville's first acting job was as an extra in the 1996 film City Hall. She had a lead role as Lyne Danner in the CBSminiseriesShake, Rattle and Roll: An American Love Story (1999), in which she also sang. In 2000, Somerville starred in the series Grosse Pointe which aired on The WB from September 2000 to February 2001.[1] The series followed the set of a fictitious WB nighttime soap, also called Grosse Pointe, and several characters were based on real-life actors.[3] Somerville played Ross Geller's girlfriend, Mona, for seven episodes in the eighth season of the NBC sitcom Friends.[1] She had small roles in films Bedazzled (2000), Spider-Man 2 (2004) and Without a Paddle (2004).
In 2003, Somerville landed a recurring role as Rachel Hoffman, a former colleague of Sandy Cohen, in the first season of Fox's teen drama series The O.C.. She appeared on the cover of Stuff magazine's May 2004 issue titled, "Girls of The O.C." and later on the cover of the magazine's November 2005 issue. In 2005, Somerville starred in the short-lived sitcom Kitchen Confidential opposite Bradley Cooper.[1] During the final season of NYPD Blue, she had a supporting role as Det. Laura Murphy, appearing in fifteen episodes. Her song "Winding Road" was included on the Garden State soundtrack, a film written and directed by Zach Braff. She sang backup vocals on Joshua Radin's first album, We Were Here (2006). Somerville was a singer in the charity cover band Band from TV with Greg Grunberg, Bob Guiney, James Denton, Hugh Laurie among others.[4]
She had guest roles on several television shows, including Gary Unmarried, Royal Pains, The Mentalist and Motive. In 2011, Somerville starred in the Hallmark Channel Christmas television film A Holiday Engagement, in which she sings the song "Angels We Have Heard On High". In 2013, Somerville played Detective Mackenzie on CBS's crime drama series Golden Boy which aired for one season. She played Dr. Christa Lorenson, a mature first-year resident, in the first season of the medical drama series Code Black. She filmed a cameo for the musical drama film A Star Is Born (2018) but her scenes were deleted.