Arvinder Singh Soin

Arvinder Singh Soin
Dr. Soin in 2021
Born (1963-01-05) 5 January 1963 (age 61)
Birmingham, United Kingdom
NationalityIndian
EducationMBBS (AIIMS), MS (AIIMS), FRCS (Edin), FRCS (Glas), FRCS (Transplant Surgery) - Cambridge, UK
Known forPioneering Liver Transplantation, Transplant surgery, Living donor liver transplantation (LDLT)
Medical career
ProfessionHepatobiliary and Liver Transplant Surgeon
InstitutionsMedanta-The Medicity,
Sir Gangaram Hospital
Sub-specialtiesPioneer in Liver Transplantation,
Transplant surgery,
Living donor liver transplantation (LDLT)
ResearchResearch in transplantation, University of Cambridge
AwardsPadma Shri, RD Birla National Award, Swasth Bharat Samman Award- Zee TV, MSOSA Award for Excellence, Medical Statesman of the Year (2012) E-MEDINEWS AWARDS
Websitelivertransplantindia.com

Dr. Arvinder Singh Soin is an Indian surgeon and the Chief Hepatobiliary and Liver Transplant Surgeon & Chairman of the Institute of Liver Transplantation and Regenerative Medicine, Medanta-The Medicity.[1] Known for his work in the field of liver transplantation, Soin also runs the Liver Transplant institute at the Sir H. N. Reliance Foundation Hospital, Mumbai. He has performed more than 3500 living donor liver transplants in India,[2] which is the highest in the country, and the second-highest in the world.[full citation needed]

Early life and education

Arvinder Singh Soin was born in Birmingham, United Kingdom in the year 1963. He went on to study medicine and surgery from India and UK. An alumnus of the All India Institute of Medical Sciences, New Delhi, where he spent 11 years gaining his MBBS and MS degrees. After which he pursued further studies to gain specialist experience in Liver and Gastrointestinal Surgery, during which he worked on the research thesis of Portal Hypertensive Gastropathy. Further, he also obtained FRCS (Fellowship of the Royal Colleges of Surgeons) degrees from both Glasgow and Edinburgh in the UK. [3]

Dr Soin was one of the first few surgeons in the UK to qualify for and obtain an Intercollegiate FRCS in Transplant Surgery. He trained and worked at the University of Cambridge for 5 years and the University of Birmingham for a year for Liver and Biliary Surgery, Liver, Kidney, Small Bowel and Pancreas transplantation.[citation needed]

Professional experience

From 2001 to 2010, he established a humongous liver transplant centre at Sir Gangaram Hospital. In June 2010, he moved with his entire team to Medanta-The Medicity, Gurgaon (Delhi-NCR), where he established a 150-bedded (including 36 Liver ICU beds) dedicated Liver Treatment facility, carrying out 250 liver transplants and hundreds of complex liver and biliary tract surgeries every year.

Research

Dr A S Soin is recognized for his research in the field of liver transplantation. In 1998, he performed the country’s first successful transplant. At Cambridge, he conducted successful research in transplantation, for which more than 110 of his original research papers and book contributions have been published in international and national journals & books.

Faculty and speaker

  • Dr Soin was a Surgical Tutor at the University of Cambridge and also a Faculty at the Royal College of Surgeons of England twice.
  • He was a visiting fellow at the Kyoto University Hospital in 1997 and Asan Medical Center, Seoul, in 2000.
  • He was a visiting faculty at the Ege University, Izmir, Turkey in 2004 and Istanbul in 2006 & 2007.
  • He is a regular Faculty member and speaker, often the only one from India, at most of the world's fora in Liver Transplantation such as ILTS, AASLD, APDW, IHPBA, IASGO, APASL, Asian Living Donor Liver Transplant Group and Asia Pacific Organ Transplant Forum.
  • Dr Soin also serves on the committees of all the important National and International Societies, as well as the National Advisory Board in Liver Transplantation.

Recognitions

  1. Awarded Padma Shri by the President of India in 2010 for pioneering the development in Liver Transplantation in India. [4]
  2. Awarded the RD Birla Outstanding Clinician of the Year Award for the year 2010 [5]
  3. Awarded the Zee TV - Swasth Bharat Samman Award for pioneering Liver Transplantation, 2011
  4. Medical Statesman of the Year - E-MEDINEWS AWARDS, 2012
  5. MSOSA Award for Excellence, 2014

Breakthrough cases

  • First successful cadaveric liver transplant in India [6]
  • First successful left lobe liver transplant in India [7]
  • First successful reduced cadaveric liver transplant in a child [8]
  • First bloodless liver transplant in India [9] [10]
  • First bloodless liver transplant in India [11]
  • India's youngest ever recipient (11 months) to receive a successful liver transplant.
  • 78-yr-old man is oldest to undergo liver transplant [12]
  • India's first successful re-transplant (on a patient a year and a half after the first) [13]
  • India's first and world's youngest Domino liver transplant [14] [15]
  • India's smallest liver transplant recipient (6kg) [16]
  • India's first (and the world's first reported) successful swap liver transplant [17] [18]
  • World's first chain of three simultaneous liver transplants (combined domino and swap) [19]
  • India's first successful Intestinal Transplant [20]

Publications

  1. Soin AS; Efficacy and safety of everolimus with reduced tacrolimus in living-donor liver transplant recipients: 12-month results of a randomized multicenter study Jun 2018[21]
  2. Soin AS; An international multicenter study of protocols for liver transplantation during a pandemic: A case for quadripartite equipoise Oct 2020[22]
  3. Soin AS; Identification of an Upper Limit of Tumor Burden for Downstaging in Candidates with Hepatocellular Cancer Waiting for Liver Transplantation: A West-East Collaborative Effort Feb 2020[23]
  4. Soin AS; Evaluation of the Intention-to-Treat Benefit of Living Donation in Patients With Hepatocellular Carcinoma Awaiting a Liver Transplant Sept 2021[24]
  5. Soin AS; Liver Transplant Outcomes in India Jan 2022[25]
  6. Soin AS; Restructuring Living-Donor Liver Transplantation at a High-Volume Center During the COVID-19 Pandemic Aug 2021[26]
  7. Soin AS; Extrahepatic Malignancies and Liver Transplantation: Current Status Aug 2021[27]
  8. Soin AS; De Novo Malignancy After Living Donor Liver Transplantation: A Large Volume Experience Oct 2020[28]
  9. Soin AS; Experience With LDLT in Patients With Hepatocellular Carcinoma and Portal Vein Tumor Thrombosis Postdownstaging Nov 2020[29]
  10. Soin AS; Outcome of hepatitis C-related liver transplantation in direct-acting antiviral era Dec 2020[30]
  11. Soin AS; Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19: A Meta-analysis Aug 2021[31]
  12. Soin AS; Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific association for the study of the liver (APASL): an update
July 2019[32]
  1. Soin AS; Liver Transplantation for Hepatocellular Carcinoma. Working Group Report from the ILTS Transplant Oncology Consensus Conference
Jun 2020[33]
  1. Soin AS; Tocilizumab plus standard care versus standard care in patients in India with moderate to severe COVID-19-associated cytokine release syndrome (COVINTOC): an open-label, multicentre, randomised, controlled, phase 3 trial May 2021[34]
  2. Soin AS, Amanjit Singh; Recanalized umbilical vein as a conduit for anterior sector venous outflow reconstruction in right lobe grafts. Surgery. 2007 Jun;141(6):830. Epub 2007 Apr 17.[35]
  3. Varma V, Gupta S, Soin A, Nundy S. Does the presence of a lump or jaundice in a patient with gall bladder cancer mean the lesion is not respectable. Dig Surg 2009; 26:306-311[36]

References

  1. ^ "Dr. AS Soin, Chairman of Liver Transplantation and Regenerative Medicine". Retrieved 29 May 2021.
  2. ^ "Dr. AS Soin - ILTS 2021". Retrieved 29 May 2021.
  3. ^ "Liver Transplant Surgery". Retrieved 29 May 2021.
  4. ^ "Padma Awards" (PDF). Ministry of Home Affairs, Government of India. 2015. Archived from the original (PDF) on 15 October 2015. Retrieved 21 July 2015.
  5. ^ "Dr Arvinder Singh Soin honoured with R D Birla Award". India Medical Times. 2011. Retrieved 21 July 2018.
  6. ^ "Padma Shri Dr Arvinder Singh Soin gets RD Birla National Award". Retrieved 8 June 2021.
  7. ^ "India's First Successful Pediatric Liver Transplant". Retrieved 8 June 2021.
  8. ^ "Liver transplant gives new lease of life to 9-year-old". Retrieved 8 June 2021.
  9. ^ "Pak boy receives first bloodless liver transplant". The Times of India. 28 April 2005. Retrieved 8 June 2021.
  10. ^ "A challenging problem". Retrieved 8 June 2021.
  11. ^ "Pak boy youngest to have liver transplant". The Times of India. 3 August 2006. Retrieved 8 June 2021.
  12. ^ "78-yr-old man is oldest to undergo liver transplant". The Times of India. 18 July 2011. Retrieved 8 June 2021.
  13. ^ "Sons donate half a liver each to dad". The Times of India. 21 March 2008. Retrieved 8 June 2021.
  14. ^ "Domino effect: Two toddlers cured with one donor liver". 20 February 2009. Retrieved 8 June 2021.
  15. ^ "Rare liver surgeries on kids". The Times of India. 20 February 2009. Retrieved 8 June 2021.
  16. ^ "2-Month-Old Nigerian Baby Undergoes Liver Transplant In Delhi". 24 October 2016. Retrieved 8 June 2021.
  17. ^ "India's first successful swap lung transplant performed at Ganga Ram Hospital". The Hindu. 20 August 2009. Retrieved 8 June 2021.
  18. ^ "Nigerian infant, Indian in swap liver transplants". The Times of India. 20 August 2009. Retrieved 8 June 2021.
  19. ^ "Six simultaneous liver transplants save lives of 3 kids". 18 January 2012. Retrieved 8 June 2021.
  20. ^ "Software engineer gets first successful intestinal transplant". The Times of India. 20 August 2009. Retrieved 8 June 2021.
  21. ^ Jeng, L. B.; Lee, S. G.; Soin, A. S.; Lee, W. C.; Suh, K. S.; Joo, D. J.; Uemoto, S.; Joh, J.; Yoshizumi, T.; Yang, H. R.; Song, G. W.; Lopez, P.; Kochuparampil, J.; Sips, C.; Kaneko, S.; Levy, G. (2018). "Efficacy and safety of everolimus with reduced tacrolimus in living-donor liver transplant recipients: 12-month results of a randomized multicenter study". American Journal of Transplantation. 18 (6): 1435–1446. doi:10.1111/ajt.14623. PMID 29237235.
  22. ^ Chew, C. A.; Iyer, S. G.; Kow AWC; Madhavan, K.; Wong AST; Halazun, K. J.; Battula, N.; Scalera, I.; Angelico, R.; Farid, S.; Buchholz, B. M.; Rotellar, F.; Chan, A. C.; Kim, J. M.; Wang, C. C.; Pitchaimuthu, M.; Reddy, M. S.; Soin, A. S.; Derosas, C.; Imventarza, O.; Isaac, J.; Muiesan, P.; Mirza, D. F.; Bonney, G. K. (2020). "An international multicenter study of protocols for liver transplantation during a pandemic: A case for quadripartite equipoise". Journal of Hepatology. 73 (4): 873–881. doi:10.1016/j.jhep.2020.05.023. PMC 7245234. PMID 32454041.
  23. ^ Lai, Q.; Vitale, A.; Halazun, K.; Iesari, S.; Viveiros, A.; Bhangui, P.; Mennini, G.; Wong, T.; Uemoto, S.; Lin, C. C.; Mittler, J.; Ikegami, T.; Zhe, Y.; Zheng, S. S.; Soejima, Y.; Hoppe-Lotichius, M.; Chen, C. L.; Kaido, T.; Lo, C. M.; Rossi, M.; Soin, A. S.; Finkenstedt, A.; Emond, J. C.; Cillo, U.; Lerut, J. (2020). "Identification of an Upper Limit of Tumor Burden for Downstaging in Candidates with Hepatocellular Cancer Waiting for Liver Transplantation: A West-East Collaborative Effort". Cancers. 12 (2): 452. doi:10.3390/cancers12020452. PMC 7072306. PMID 32075133.
  24. ^ Lai, Q.; Sapisochin, G.; Gorgen, A.; Vitale, A.; Halazun, K. J.; Iesari, S.; Schaefer, B.; Bhangui, P.; Mennini, G.; Wong TCL; Uemoto, S.; Lin, C. C.; Mittler, J.; Ikegami, T.; Yang, Z.; Frigo, A. C.; Zheng, S. S.; Soejima, Y.; Hoppe-Lotichius, M.; Chen, C. L.; Kaido, T.; Lo, C. M.; Rossi, M.; Soin, A. S.; Finkenstedt, A.; Emond, J. C.; Cillo, U.; Lerut, J. P. (2021). "Evaluation of the Intention-to-Treat Benefit of Living Donation in Patients With Hepatocellular Carcinoma Awaiting a Liver Transplant". JAMA Surgery. 156 (9): e213112. doi:10.1001/jamasurg.2021.3112. PMC 8281041. PMID 34259797.
  25. ^ Choudhary, N. S.; Bhangui, P.; Soin, A. S. (2022). "Liver Transplant Outcomes in India". Clinical Liver Disease. 19 (1): 32–35. doi:10.1002/cld.1166. PMC 8785916. PMID 35106148.
  26. ^ Soin, A. S.; Choudhary, N. S.; Yadav, S. K.; Saigal, S.; Saraf, N.; Rastogi, A.; Bhangui, P.; Srinivasan, T.; Mohan, N.; Saha, S. K.; Gupta, A.; Chaudhary, R. J.; Yadav, K.; Dhampalwar, S.; Govil, D.; Gupta, N.; Vohra, V. (2021). "Restructuring Living-Donor Liver Transplantation at a High-Volume Center During the COVID-19 Pandemic". Journal of Clinical and Experimental Hepatology. 11 (4): 418–423. doi:10.1016/j.jceh.2020.09.009. PMC 7543734. PMID 33052181. Retrieved 2 June 2022.
  27. ^ Choudhary, N. S.; Saigal, S.; Saraf, N.; Soin, A. S. (2021). "Extrahepatic Malignancies and Liver Transplantation: Current Status". Journal of Clinical and Experimental Hepatology. 11 (4): 494–500. doi:10.1016/j.jceh.2020.10.008. PMC 8267344. PMID 34276155.
  28. ^ Tiwari, A.; Saigal, S.; Choudhary, N. S.; Saha, S.; Rastogi, A.; Bhangui, P.; Saraf, N.; Srinivasan, T.; Yadav, S. K.; Gautam, D.; Nundy, S.; Soin, A. S. (2020). "De Novo Malignancy After Living Donor Liver Transplantation: A Large Volume Experience". Journal of Clinical and Experimental Hepatology. 10 (5): 448–452. doi:10.1016/j.jceh.2020.02.001. PMC 7527845. PMID 33029053.
  29. ^ Soin, A. S.; Bhangui, P.; Kataria, T.; Baijal, S. S.; Piplani, T.; Gautam, D.; Choudhary, N. S.; Thiagarajan, S.; Rastogi, A.; Saraf, N.; Saigal, S. (2020). "Experience With LDLT in Patients With Hepatocellular Carcinoma and Portal Vein Tumor Thrombosis Postdownstaging". Transplantation. 104 (11): 2334–2345. doi:10.1097/TP.0000000000003162. PMID 32032291. S2CID 211064901. Retrieved 2 June 2022.
  30. ^ Choudhary, N. S.; Saraf, N.; Saigal, S.; Rastogi, A.; Bhangui, P.; Thiagrajan, S.; Soin, A. S. (2020). "Outcome of hepatitis C-related liver transplantation in direct-acting antiviral era". Indian Journal of Gastroenterology. 39 (6): 539–543. doi:10.1007/s12664-020-01105-z. PMID 33230754. S2CID 227133960. Retrieved 2 June 2022.
  31. ^ WHO Rapid Evidence Appraisal for COVID-19 Therapies (REACT) Working Group; et al. (2021). "Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19: A Meta-analysis". JAMA. 326 (6): 499–518. doi:10.1001/jama.2021.11330. hdl:1854/LU-8716283. PMC 8261689. PMID 34228774.{{cite journal}}: CS1 maint: numeric names: authors list (link)
  32. ^ Sarin, S. K.; et al. (2019). "Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific association for the study of the liver (APASL): an update". Hepatology International. 13 (4): 353–390. doi:10.1007/s12072-019-09946-3. PMC 6728300. PMID 31172417.
  33. ^ Sarin, S. K.; et al. (2019). "Liver Transplantation for Hepatocellular Carcinoma. Working Group Report from the ILTS Transplant Oncology Consensus Conference". Hepatology International. 13 (4): 353–390. doi:10.1007/s12072-019-09946-3. PMC 6728300. PMID 31172417.
  34. ^ Sarin, S. K.; et al. (2019). "Tocilizumab plus standard care versus standard care in patients in India with moderate to severe COVID-19-associated cytokine release syndrome (COVINTOC): an open-label, multicentre, randomised, controlled, phase 3 trial". Hepatology International. 13 (4): 353–390. doi:10.1007/s12072-019-09946-3. PMC 6728300. PMID 31172417.
  35. ^ "Recanalized umbilical vein as a conduit for anterior sector venous outflow reconstruction in right lobe grafts". Retrieved 29 May 2021. {{cite journal}}: Cite journal requires |journal= (help)
  36. ^ Varma, V.; Gupta, S.; Soin, A. S.; Nundy, S. (2009). "Does the presence of jaundice and/or a lump in a patient with gall bladder cancer mean that the lesion is not resectable?". Digestive Surgery. 26 (4): 306–311. doi:10.1159/000231880. PMID 19657192. S2CID 22345979. Retrieved 29 May 2021.