Adenolipoma

Adenolipoma
Other namesLipoadenoma, peri-sudoral lipoma
Microscopic image of a thyroid adenolipoma
Microscopic image of a thyroid adenolipoma
SymptomsSmall lump, difficulty breathing
TypesThyroid adenolipoma, skin adenolipoma
Diagnostic methodSurgical resection
TreatmentSurgical excision
PrognosisVery good - surgery is curative

An adenolipoma is a type of lipoma (benign fat tumor) that develops in the eccrine sweat glands. They can occur either in the skin,[1] or in the thyroid. [2]

Signs and symptoms

Adenolipomas are usually asymptomatic, soft nodules that aren't tender, and are slow-growing.[3] In the case of thyroid adenolipomas, breathing restrictions may be present.[4]

Causes

The cause of adenolipomas is unknown. Theories include improper development in the embryo and invasion from connective tissue.[5]

Diagnosis

Adenolipomas are diagnosed by surgical resection and examining the tumor with a microscope.[5] The presence of eccrine sweat glands are used to distinguish the tumor from a common lipoma. Size and the development of the capsule (tissue surrounding the tumor) can also aid in diagnosis. [6]

Treatment

Adenolipomas are benign tumors, meaning they have no potential to become malignant (cancerous). Surgery is curative,[1] however, adenolipomas can reoccur.[4]

History

Adenolipomas are a relatively recent diagnosis, being first described by Hitchcock et al. in 1993 in a case series. Ait-Ourhrouil and Grosshans later made another case series, disagreeing with the given name and proposing the term peri-sudoral lipoma.[1]

References

  1. ^ a b c Amir, Rawan; Sheikh, Salwa (2018-04-05). "Adenolipoma of the Skin: A Report of 11 Cases". Case Reports in Dermatology. 10 (1): 76–81. doi:10.1159/000488341. ISSN 1662-6567. PMC 5968233. PMID 29805368.
  2. ^ Joon, Pawan; Weerakkody, Yuranga (2014-10-09), "Adenolipoma (thyroid gland)", Radiopaedia.org, doi:10.53347/rid-31440, S2CID 239518259, retrieved 2023-02-27
  3. ^ AbdullGaffar, Badr; Raman, Lakshmiah G.; Prince, Sheela (June 2014). "Dermal Spindle Cell Adenolipoma". The American Journal of Dermatopathology. 36 (6): 527–529. doi:10.1097/DAD.0b013e31829871bd. ISSN 0193-1091. PMID 23974223.
  4. ^ a b Hjorth, L.; Thomsen, L.B.; Nielsen, V.T. (January 1986). "Adenolipoma of the thyroid gland". Histopathology. 10 (1): 91–96. doi:10.1111/j.1365-2559.1986.tb02463.x. PMID 3957249. S2CID 33232810 – via Wiley Online Library.
  5. ^ a b "Adenolipoma". www.pathologyoutlines.com. Retrieved 2023-02-27.
  6. ^ Agua, C. Del; Felipo, F. (2004). "Adenolipoma of the skin". Dermatology Online Journal. 10 (2): 9. doi:10.5070/D30fh507g3. PMID 15530299.

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