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Singles
2021 Andalucía Open
Final
Champion	Pablo Carreño Busta
Runner-up	Jaume Munar
Score	6–1, 2–6, 6–4
Details
Draw	28
Seeds	8
Events
Singles Doubles
Andalucía Open · 2022 →

Pablo Carreño Busta defeated Jaume Munar in the final, 6–1, 2–6, 6–4 to win the inaugural Men's Singles tennis title at the 2021 Andalucía Open. Notably, this was the first tournament in ATP history to feature 4 semifinalists from the same nation.

This was the first edition of the tournament, primarily organised due to the cancellation of some tournaments in 2021, due to the COVID-19 pandemic.^[1]

The top four seeds received a bye into the second round.

	Semifinals							Final
	1	Pablo Carreño Busta	6	3	77
	4	Albert Ramos Viñolas	1	6	65
								1	Pablo Carreño Busta	6	2	6
									Jaume Munar	1	6	4
	WC	Carlos Alcaraz	64	4
		Jaume Munar	77	6

	First round							Second round							Quarterfinals							Semifinals
								1	P Carreño Busta	77	6
	Q	B Zapata Miralles	2	3				Q	M Vilella Martínez	62	3
	Q	M Vilella Martínez	6	6											1	P Carreño Busta	6	6
		F Bagnis	6	77											7	S-w Kwon	4	0
		F Cerúndolo	3	62					F Bagnis	1	3
	WC	H Rune	3	6	64			7	S-w Kwon	6	6
	7	S-w Kwon	6	3	77																	1	P Carreño Busta	6	3	77
																						4	A Ramos Viñolas	1	6	65
								4	A Ramos Viñolas	6	4	6
		L Pouille	4	77	5				R Berankis	3	6	3
		R Berankis	6	65	7										4	A Ramos Viñolas	64	7	6
		N Gombos	63	6	6											N Gombos	77	5	4
		JI Londero	77	1	3				N Gombos	5	77	77
		R Carballés Baena	5	1				8	F Delbonis	7	64	61
	8	F Delbonis	7	6

	First round							Second round							Quarterfinals							Semifinals
	6	F López	6	6
		T Daniel	4	4				6	F López	6	2	4
	Q	N Milojević	63	3				WC	C Alcaraz	4	6	6
	WC	C Alcaraz	77	6											WC	C Alcaraz	6	6
		M Kukushkin	5	3											3	C Ruud	2	4
		G Mager	7	6					G Mager	3	2
								3	C Ruud	6	6
																						WC	C Alcaraz	64	4
	5	A Davidovich Fokina	61	6	6																		J Munar	77	6
		D Džumhur	77	2	2			5	A Davidovich Fokina	1	3
		I Ivashka	6	77					I Ivashka	6	6
		P Martínez	3	62												I Ivashka	77	4	4
	Q	H Laaksonen	4	1												J Munar	65	6	6
		J Munar	6	6					J Munar	6	6
								2/WC	F Fognini	2	1

	First round							Qualifying competition
	1	Evgeny Donskoy	6	6
	WC	Leo Borg	1	0
								1	Evgeny Donskoy	1	4
								5	Bernabé Zapata Miralles	6	6
		Ernests Gulbis	2	1
	5	Bernabé Zapata Miralles	6	6

	First round							Qualifying competition
	2	Peter Gojowczyk	2	3
		Steven Diez	6	6
									Steven Diez	5	3
								6	Nikola Milojević	7	6
		Alessandro Giannessi	77	3	1r
	6	Nikola Milojević	64	6	4

	First round							Qualifying competition
	3	Antoine Hoang	2	4
	Alt	Mario Vilella Martínez	6	6
								Alt	Mario Vilella Martínez	6	3	6
								WC	Carlos Gómez-Herrera	3	6	3
	WC	Carlos Gómez-Herrera	6	6
	7	Martin Kližan	4	1

	First round							Qualifying competition
	4	Henri Laaksonen	6	67	6
		Roman Safiullin	3	79	1
								4	Henri Laaksonen	7	3	6
								8	Lorenzo Giustino	5	6	1
	Alt	Roberto Marcora	64	4
	8	Lorenzo Giustino	77	6

• Main draw
• Qualifying draw