The 2021–22 season was the 103rd season in the existence of Hamburger SV and the club's fourth consecutive season in the second division of German football. In addition to the domestic league, Hamburger SV participated in this season's edition of the DFB-Pokal.
Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply. Players may hold more than one non-FIFA nationality.
Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply. Players may hold more than one non-FIFA nationality.
As a result of their third place finish in the regular season, the club qualified for the play-off match with the 16th-place team in the 2021–22 Bundesliga to determine whether the club would be promoted to the 2022–23 Bundesliga.