2010 Mercury Insurance Open
Date	August 2–8
Edition	30th
Category	WTA Premier
Draw	28S /16D
Prize money	$700,000
Surface	Hard / outdoor
Location	San Diego, California, U.S.
Champions
Singles
Svetlana Kuznetsova
Doubles
Maria Kirilenko / Zheng Jie
← 2007 · Southern California Open · 2011 →

The 2010 Mercury Insurance Open was a women's tennis tournament played on outdoor hard courts. It was the first edition of the Southern California Open since the tournament left the tour in 2007. It was classified as one of the WTA Premier tournaments of the 2010 WTA Tour. It was played in San Diego, California, United States. Unseeded Svetlana Kuznetsova won the singles title.

Svetlana Kuznetsova defeated Agnieszka Radwańska, 6–4, 6–7^(7–9), 6–3

• It was Kuznetsova's first title of the year and 13th of her career.

Maria Kirilenko / Zheng Jie defeated Lisa Raymond / Rennae Stubbs, 6–4, 6–4

Player	Nationality	Ranking*	Seed
Jelena Janković	Serbia	2	1
Samantha Stosur	Australia	5	2
Vera Zvonareva	Russia	9	3
Agnieszka Radwańska	Poland	11	4
Flavia Pennetta	Italy	12	5
Marion Bartoli	France	14	6
Shahar Pe'er	Israel	16	7
Yanina Wickmayer	Belgium	17	8

• Seedings are based on the rankings of July 26, 2010.

The following players received wildcards into the singles main draw:

• Dominika Cibulková
• Gisela Dulko
• Ana Ivanovic

The following players received entry from the qualifying draw:

• Kurumi Nara
• Shenay Perry
• Chanelle Scheepers
• CoCo Vandeweghe

The following player received entry by a lucky loser spot:

• Jamie Hampton

• Official website
• ITF tournament edition details
• WTA tournament draws