The 1950 Kansas Jayhawks football team represented the University of Kansas in the Big Seven Conference during the 1950 college football season. In their third season under head coach Jules V. Sikes, the Jayhawks compiled a 6–4 record (3–3 against conference opponents), finished fourth in the Big Seven Conference, and outscored all opponents by a combined total of 284 to 188.^[1][2] They played their home games at Memorial Stadium in Lawrence, Kansas.

The team's statistical leaders included Wade Stinson with 1,129 rushing yards (the program's first 1,000-yard rusher) and 84 points scored,^[3] and Chet Strehlow with 651 passing yards.^[4] John Amberg and Mike McCormack were the team captains.^[2] Other notable members of the team included George Mrkonic.

Date	Opponent	Rank	Site	Result	Attendance	Source
September 23	TCU*		Memorial Stadium Lawrence, KS	L 7–14	32,000
September 29	at Denver*		DU Stadium Denver, CO	W 46–6	14,218	[5]
October 7	Colorado		Memorial Stadium Lawrence, KS	W 27–21	24,000–25,000
October 14	at Iowa State		Clyde Williams Field Ames, IA	W 33–21	17,392
October 21	Oklahoma A&M*		Memorial Stadium Lawrence, KS	W 40–7	22,500
October 28	Nebraska		Memorial Stadium Lawrence, KS (rivalry)	L 26–33	39,000
November 4	at Utah*		Ute Stadium Salt Lake City, UT	W 39–26	13,000
November 11	No. 3 Oklahoma	No. 19	Memorial Stadium Lawrence, KS	L 13–33	37,621	[6]
November 18	at Kansas State		Memorial Stadium Manhattan, KS (rivalry)	W 47–7	18,000
November 23	at Missouri		Memorial Stadium Columbia, MO (Border War)	L 6–20	18,000
*Non-conference game Homecoming Rankings from AP Poll released prior to the game