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1920 United States Senate election in Missouri
← 1918 (special) 1926 (special) →
	County results; Spencer: 40–50% 50–60% 60–70% 70–80% 80–90%; Long: 40–50% 50–60% 60–70% 70–80% 80–90%
U.S. senator before election; Selden P. Spencer; Republican	Elected U.S. senator ; Selden P. Spencer; Republican

The 1920 United States Senate election in Missouri took place on November 2, 1920 in Missouri. The incumbent Republican Senator, Selden P. Spencer, was re-elected to a full term, having won a special election in 1918. He defeated Breckinridge Long of the Democratic Party. Spencer underperformed Republican presidential nominee Warren G. Harding, who won 54.6% of the vote in the concurrent presidential election.

Democratic primary

Democratic primary August 3, 1920^[3]
Party		Candidate	Votes	%
	Democratic	Breckinridge Long	65,825	37.40
	Democratic	Charles M. Hay	44,504	25.29
	Democratic	Henry Samuel Priest	40,637	23.09
	Democratic	Arthur N. Lindsey	15,631	8.88
	Democratic	John C. Higdon	5,998	3.41
	Democratic	George H. Scruton	3,407	1.94
Total votes			176,002	100

Republican primary August 3, 1920^[3]
Party		Candidate	Votes	%
	Republican	Selden P. Spencer	95,867	49.74
	Republican	Dwight F. Davis	73,541	38.16
	Republican	James L. Minnis	23,341	12.11
Total votes			192,729	100

The Farmer–Worker Party nominated carpenter W. J. Mallett.^[4]

Socialist primary August 3, 1920^[3]
Party		Candidate	Votes	%
	Socialist	Elias F. Hodges	1,515	100
Total votes			1,515	100

The Socialist Labor Party nominated Andrew Trudell.

1920 United States Senate election in Missouri^[5]
Party		Candidate	Votes	%	±%
	Republican	Selden P. Spencer (Incumbent)	711,161	53.65%	+1.26
	Democratic	Breckinridge Long	589,498	44.47%	−1.82
	Socialist	Elias F. Hodges	1,807	0.18%	−1.33
	Farmer–Worker	W. J. Mallett	3,158	0.24%	+0.24
	Socialist Labor	Andrew Trudell	1,675	0.13%	−0.03
Majority			121,663	9.18%
Turnout			1,325,494
	Republican hold		Swing

^ ^a ^b ^c ^d ^e "RECORD OF CANDIDATES WHO ARE LOOKING FOR SENATORIAL HONORS". St. Louis Post-Dispatch. St. Louis, Missouri. August 1, 1920. pp. 1B–4B. Retrieved July 23, 2023 – via State Historical Society of Missouri.
^ "Higdon Runs as a "Wet"". Farmington Times. Farmington, Missouri. April 23, 1920. p. 2. Retrieved July 23, 2023 – via State Historical Society of Missouri.
^ ^a ^b ^c Official Manual of the State of Missouri 1921 - 1922. Missouri Secretary of State's Office. 1922. p. 490. Retrieved July 23, 2023.
^ "MONETT MAN ON FARMER–LABOR TICKET". Monett Times. Monett, Missouri. August 20, 1920. p. 4. Retrieved July 23, 2023 – via State Historical Society of Missouri.
^ "Statistics of the Congressional Election of November 2, 1920" (PDF). Clerk.house.gov. p. 9. Retrieved August 21, 2019.