كتلة التمايز 86

كتلة التمايز 86
معلومات عامة
جزء من
وُجد في الأصنوفة
يشفر بـ
الوظيفة الجزيئية
مكون الخلية
العملية الحيوية
يتفاعل مادياً مع
له جزء أو أجزاء
CD86 molecule
PDB rendering based on 1i85.
التراكيب المتوفرة
بنك بيانات البروتين بحث أورثولوغ: PDBe, RCSB
المعرفات
الرمز، (أو الرموز) CD86; B7-2; B7.2; B70; CD28LG2; LAB72
معرفات خارجية OMIM601020 MGI101773 هومولوجين10443 بطاقات الجينات: CD86 Gene
نمط التعبير عن الحمض النووي الريبوزي
مصادر أخرى عن بيانات أنماط التعبير
التقويمات
الأنواع الإنسان الفأر
أنتريه 942 12524
انسمبل ENSG00000114013 ENSMUSG00000022901
يونيبروت P42081 P42082
قاعدة بيانات مرجعية (مرسال ر.ن.ا) NM_001206924 NM_019388
قاعدة بيانات مرجعية (بروتين) NP_001193853 NP_062261
الموقع (متصفح جينوم جامعة كاليفورنيا سانتا كروز  [لغات أخرى]‏) Chr 3:
122.06 – 122.12 Mb
Chr 16:
36.6 – 36.67 Mb
بحث ببمد [1] [2]

كتلة التمايز 86 (CD86 أو B7-2) هو بروتين يبرز على الخلية المقدمة للمستضد ليوفر إشارات تحفيز مرافق لتحفيز وحياة الخلية التائية.[24][25] كتلة التمايز 86 تمثل ربيطة للبروتين المرتبط بالخلايا اللمفاوية التائية السامة 4 وكتلة التمايز 28.

كتلة التمايز 86 تعمل ترادفيا مع كتلة التمايز 80.

مراجع

  1. ^ ا ب ج د ه و "InterPro Release 71.0". 8 نوفمبر 2018.
  2. ^ ا ب مذكور في: يونيبروت. الوصول: 13 نوفمبر 2019. معرف يونيبروت: P42081. لغة العمل أو لغة الاسم: الإنجليزية.
  3. ^ ا ب Barbara Bierer (29 Jan 1999). "CD80 and CD86 are not equivalent in their ability to induce the tyrosine phosphorylation of CD28" (بالإنجليزية). pp. 3116–24. Retrieved 2019-04-08.
  4. ^ ا ب ج د ه و "GOA". اطلع عليه بتاريخ 2019-04-08.
  5. ^ Barbara Bierer (29 Jan 1999). "CD80 and CD86 are not equivalent in their ability to induce the tyrosine phosphorylation of CD28" (بالإنجليزية). pp. 3116–24. Retrieved 2019-04-08.
  6. ^ Steven C. Almo (29 Mar 2001). "Structural basis for co-stimulation by the human CTLA-4/B7-2 complex" (بالإنجليزية). pp. 604–8. Retrieved 2019-04-08.
  7. ^ "Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network" (بالإنجليزية). 5 Dec 2014. pp. 5339–46. Retrieved 2019-04-08.
  8. ^ ا ب ج د ه و ز ح ط ي يا "GOA". اطلع عليه بتاريخ 2017-10-31.
  9. ^ "GOA". اطلع عليه بتاريخ 2018-01-01.
  10. ^ Gordon J. Freeman (5 Nov 1993). "Cloning of B7-2: a CTLA-4 Counter-Receptor That Costimulates Human T Cell Proliferation" (بالإنجليزية). pp. 909–11. Retrieved 2019-04-08.
  11. ^ "GOA". اطلع عليه بتاريخ 2017-10-31.
  12. ^ ا ب Barbara Bierer (29 Jan 1999). "CD80 and CD86 are not equivalent in their ability to induce the tyrosine phosphorylation of CD28" (بالإنجليزية). pp. 3116–24. Retrieved 2017-10-31.
  13. ^ "GOA". اطلع عليه بتاريخ 2019-04-08.
  14. ^ "Molecular cloning and expression of early T cell costimulatory molecule-1 and its characterization as B7-2 molecule" (بالإنجليزية). 15 May 1994. pp. 4929–36. Retrieved 2019-04-08.
  15. ^ "Mycobacterium tuberculosis infection of human dendritic cells decreases integrin expression, adhesion and migration to chemokines" (بالإنجليزية). Jan 2014. pp. 39–51. Retrieved 2017-10-31.
  16. ^ Graça Raposo (Jul 2005). "Exosomal-like vesicles are present in human blood plasma" (بالإنجليزية). pp. 879–87. Retrieved 2017-10-31.
  17. ^ Sonja I Buschow (2010). "MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis" (بالإنجليزية). pp. 851–6. Retrieved 2017-10-31.
  18. ^ ا ب Michael S Livstone (27 أغسطس 2011). "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium". ص. 449–462. اطلع عليه بتاريخ 2019-04-08.
  19. ^ "Mycobacterium tuberculosis infection of human dendritic cells decreases integrin expression, adhesion and migration to chemokines" (بالإنجليزية). Jan 2014. pp. 39–51. Retrieved 2019-04-08.
  20. ^ Graça Raposo (Jul 2005). "Exosomal-like vesicles are present in human blood plasma" (بالإنجليزية). pp. 879–87. Retrieved 2019-04-08.
  21. ^ Sonja I Buschow (2010). "MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis" (بالإنجليزية). pp. 851–6. Retrieved 2019-04-08.
  22. ^ "GOA". اطلع عليه بتاريخ 2017-10-31.
  23. ^ "Open Targets Platform". اطلع عليه بتاريخ 2023-08-14.
  24. ^ Chen C، Gault A، Shen L، Nabavi N (مايو 1994). "Molecular cloning and expression of early T cell costimulatory molecule-1 and its characterization as B7-2 molecule". Journal of Immunology. ج. 152 ع. 10: 4929–36. PMID:7513726.
  25. ^ "Entrez Gene: CD86 CD86 molecule". مؤرشف من الأصل في 2010-12-05.


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