Diapedesis

Diapedesis Neutrofil dari pembuluh darah ke tempat cedera jaringan atau infeksi selama Respon imun bawaan.

Diapedesis adalah kemampuan untuk menembus keluar pori-pori membran kapiler dan menuju ke jaringan. Dalam tubuh manusia kemampuan diapedesis ini dimiliki oleh sel darah putih (leukosit).[1]

Mekanisme

Perekrutan leukosit dari aliran darah ke jaringan adalah langkah kunci dalam pengawasan kekebalan dan pertahanan inang terhadap patogen. Ini juga merupakan faktor penting dalam peradangan akut dan kronis. Oleh karena itu, penjelasan peristiwa molekuler yang mendasari emigrasi leukosit ke jaringan dalam keadaan fisiologis dan patologis penting dalam memahami mekanisme penyakit dan dalam merancang terapi baru.[2]

Referensi

  1. ^ Kompasiana.com (2017-11-25). "Diapedesis (Kemampuan Menembus)". KOMPASIANA. Diakses tanggal 2020-08-01. 
  2. ^ Arnaout, M. Amin (1998). Jameson, J. Larry, ed. Principles of Molecular Medicine (dalam bahasa Inggris). Totowa, NJ: Humana Press. hlm. 641–649. doi:10.1007/978-1-59259-726-0_65. ISBN 978-1-59259-726-0. 

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