甘氨酰缬氨酰甘氨酸

甘氨酰缬氨酰甘氨酸
别名 N-(N-甘氨酰缬氨酰)甘氨酸
识别
CAS号 28112-97-2（S）  checkY
性质
化学式 C9H17N3O4
摩尔质量 231.25 g·mol−1
若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

甘氨酰缬氨酰甘氨酸（Gly-Val-Gly）是一种三肽，化学式为C9H17N3O4。它可以甘氨酸苄酯对甲苯磺酸盐和叔丁氧羰基-L-缬氨酸为原料，经多步反应制得，[1]它在水中结晶可以得到一水合物。[2]它可以和N-溴代丁二酰亚胺反应，得到甲醛和异丁醛。[3]

参考文献

  1. ^ Gowda, B K Kempe; Rangappa, K S; Gowda, D Channe. Kinetic studies on oxidation of Gly-Val-Gly, Gly-Phe-Gly and Ala-Val-Gly using Mn(III) （页面存档备份，存于互联网档案馆）. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (2002), 41B (5), 1039-1044.
  2. ^ Jin L. Liu, Andrew W. Hakin, Gavin R. Hedwig. Volumetric properties of tripeptides with non-polar side-chains: Partial molar volumes at T=(288.15 to 313.15) K and partial molar expansions at T = 298.15 K of some peptides of sequence gly-X-gly in aqueous solution. The Journal of Chemical Thermodynamics, 2009. 41 (11): 1232-1238. doi:10.1016/j.jct.2009.05.011.
  3. ^ Kumara, M. N.; Linge Gowda, N. S.; Mantelingu, K.; Rangappa, Kanchugara Koppal S. N-Bromosuccinimide assisted oxidation of tripeptides and their amino acid analogs: synthesis, kinetics, and product studies. Journal of Molecular Catalysis A: Chemical (2009), 309(1-2), 172-177. doi:10.1016/j.molcata.2009.05.024.