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SOX9

SOX9
已知的結構
PDB直系同源搜索: PDBe RCSB
識別號
别名SOX9;, CMD1, CMPD1, SRA1, SRXX2, SRXY10, SRY-box 9, SRY-box transcription factor 9
外部IDOMIM608160 MGI98371 HomoloGene294 GeneCardsSOX9
基因位置(人类
17號染色體
染色体17號染色體[1]
17號染色體
SOX9的基因位置
SOX9的基因位置
基因座17q24.3起始72,121,020 bp[1]
终止72,126,416 bp[1]
RNA表达模式


查阅更多表达数据
直系同源
物種人類小鼠
Entrez
Ensembl
UniProt
mRNA​序列

NM_000346

NM_011448

蛋白序列

NP_000337

NP_035578

基因位置​(UCSC)Chr 17: 72.12 – 72.13 MbChr 11: 112.67 – 112.68 Mb
PubMed​查找[3][4]
維基數據
檢視/編輯人類檢視/編輯小鼠

SOX9(英語:Transcription factor SOX-9)是一种转录因子,由人类基因Sox9编码,是塞爾托利氏細胞等细胞的标志物[5][6]

相互作用

SOX9可與类固醇生成因子1MED12[7]MAF[8]發生相互作用

参考文献

  1. ^ 1.0 1.1 1.2 GRCh38: Ensembl release 89: ENSG00000125398 - Ensembl, May 2017
  2. ^ 2.0 2.1 2.2 GRCm38: Ensembl release 89: ENSMUSG00000000567 - Ensembl, May 2017
  3. ^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  4. ^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine. 
  5. ^ Tommerup N, Schempp W, Meinecke P, Pedersen S, Bolund L, Brandt C, et al. Assignment of an autosomal sex reversal locus (SRA1) and campomelic dysplasia (CMPD1) to 17q24.3-q25.1. Nature Genetics. June 1993, 4 (2): 170–4. PMID 8348155. S2CID 12263655. doi:10.1038/ng0693-170. 
  6. ^ Entrez Gene: SOX9 SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal). [2021-06-01]. (原始内容存档于2010-03-07). 
  7. ^ Zhou R, Bonneaud N, Yuan CX, de Santa Barbara P, Boizet B, Schomber T, et al. SOX9 interacts with a component of the human thyroid hormone receptor-associated protein complex. Nucleic Acids Research. July 2002, 30 (14): 3245–52. PMC 135763可免费查阅. PMID 12136106. doi:10.1093/nar/gkf443. 
  8. ^ Huang W, Lu N, Eberspaecher H, De Crombrugghe B. A new long form of c-Maf cooperates with Sox9 to activate the type II collagen gene. The Journal of Biological Chemistry. December 2002, 277 (52): 50668–75. PMID 12381733. doi:10.1074/jbc.M206544200可免费查阅. 

外部链接


SOX9引用了美国国家医学图书馆提供的資料,这些資料属于公共领域

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