MA-10細胞

MA-10細胞（以建立者Mario Ascoli首字母命名[1]）是生物医学研究（英语：biomedical research）中最常用的间质细胞（Leydig cell）肿瘤细胞系[2]，来源于C57BL/6J近交系小鼠。MA-10細胞特点为需要黄体生成素（LH）刺激来生成类固醇，对研究甾体激素的形成与调控很有帮助[3]

参考文献

  1. ^ ASCOLI, MARIO. Characterization of several clonal lines of cultured Leydig tumor cells: gonadotropin receptors and steroidogenic responses. Endocrinology. 1 Jan 1981, 108 (1): 88–95. PMID 6257492. doi:10.1210/endo-108-1-88. 
  2. ^ Zirkin BR, Papadopoulos V. Leydig cells: formation, function, and regulation. Biology of Reproduction. 2018, 99 (1): 101–11. PMC 6044347 可免费查阅. PMID 29566165. doi:10.1093/biolre/ioy059. 
  3. ^ Rahman, Nafis A; Huhtaniemi, Ilpo T. Testicular cell lines. Mol Cell Endocrinol. 30 December 2004, 228 (1-2): 53–65. PMID 15541572. doi:10.1016/j.mce.2003.05.001. 

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