4-吡啶乙酸是一种有机化合物,化学式为C7H7NO2,它是三种吡啶乙酸的同分异构体之一。
合成与反应
4-吡啶乙酸可由4-甲基吡啶和钠在液氨中反应,再与二氧化碳反应后酸化制得。[2]
它和乙醇在硫酸催化下回流,可以得到4-吡啶乙酸乙酯。[3]
参考文献
- ^ "PhysProp" data were obtained from Syracuse Research Corporation of Syracuse, New York (US). Retrieved from SciFinder. [2024-11-06].
- ^ George W. Headley; Marion H. O'Leary. Solvent dependence of oxygen isotope effects on the decarboxylation of 4-pyridylacetic acid. J. Am. Chem. Soc. 1990, 112, 5, 1894–1896. doi:10.1021/ja00161a038.
- ^ Pranjal K. Baruah; et al. Synthesis, anticonvulsant activity, and neuropathic pain-attenuating activity of N-benzyl 2-amino-2-(hetero)aromatic acetamides. Bioorganic & Medicinal Chemistry, 2012. 20 (11): 3551-3564. doi:10.1016/j.bmc.2012.04.002.