Арлін Шарп

Арлін Шарп
Народилася1953
Країна США
Діяльністьімунологиня
Alma materГарвардська медична школаd
Гарвардський університет
Галузьімунологія
ЧленствоНаціональна академія наук США
Нагороди

Арлін Гелен Шарп (англ. Arlene Helen Sharpe, народилася в 1953 році) — американський імунолог, професор порівняльної патології Джорджа Фабіана Гарвардської медичної школи. Розкрила механізм роботи білка-імуноглобуліну PDCD1, що програмують клітинну смерть[1].

Арлін Шарп здобула диплом бакалавра з біохімії у коледжі Редкліфф, ступінь доктора медицини здобула у Гарвардському університеті (Гарвардська медична школа), в 1982 році, та Ph. D. з мікробіології в 1981 році.

Нагороди та визнання

Доробок

  • mit A. K. Abbas: T-cell stimulation: an abundance of B7s, Nat Med., Band 5, Dezember 1999, S. 1345–1346.
  • mit Gordon Freeman, Tasuku Honjo u. a.: Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte Activation, J. Exp. Medicine, Band 192, 2000, S. 1027
  • mit Gordon Freeman: The B7–CD28 superfamily, Nature Reviews Immunology, Band 2, 2002, S. 116–126
  • mit Yvette Latchman, Honjo, Freeman u. a.: PD-L2 is a second ligand for PD-1 and inhibits T cell activation, Nature Immunology, Band 2, 2001, S. 261–268
  • mit E. John Wherry, Rafi Ahmed, Gordon Freeman: The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection, Nature Immunology, Band 8, 2007, S. 239–245
  • mit S. H. Baumeister, G. J. Freeman, G. Dranoff: Coinhibitory Pathways in Immunotherapy for Cancer, Annual Review of Immunology, Band 34, 2016, S. 539–573
  • mit P. T. Sage: T follicular regulatory cells, Immunol Rev., Band 271, 2016, S. 246–259
  • mit S. L. McArdel, C. Terhorst: Roles of CD48 in regulating immunity and tolerance, Clin Immunol., Band 164, 2016, S. 10–20

Примітки

  1. ↑ Нобелевская премия за голодные эксперименты [Архівовано 30 липня 2018 у Wayback Machine.](рос.)

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