Četica prepoznavanja signala

Četica prepoznavanja signala
Identifikatori
EC broj3.6.5.4
Baze podataka
IntEnzIntEnz pregled
BRENDABRENDA pristup
ExPASyNiceZyme pregled
KEGGKEGG pristup
MetaCycmetabolički put
PRIAMprofil
Strukture PBPRCSB PDB PDBe PDBj PDBsum

Četica prepoznavanja signala (EC 3.6.5.4) je enzim sa sistematskim imenom GTP fosfohidrolaza (pomoć pri proteinskoj sintezi).[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju

GTP + H2O GDP + fosfat

Dejstvo ovih enzima je vezano za prepoznavanje signalnih čestica.

Reference

  1. ^ Connolly, T. & Gilmore, R. (1989). „The signal recognition particle receptor mediates the GTP-dependent displacement of SRP from the signal sequence of the nascent polypeptide”. Cell. 57: 599—610. PMID 2541918. 
  2. ^ Connolly, T., Rapiejko, P.J. and Gilmore, R. (1991). „Requirement of GTP hydrolysis for dissociation of the signal recognition particle from its receptor”. Science. 252: 1171—1173. PMID 1851576. 
  3. ^ Miller, J.D., Wilhelm, H., Gierasch, L., Gilmore, R. and Walter, P. (1993). „GTP binding and hydrolysis by the signal recognition particle during initiation of protein translocation”. Nature. 366: 351—354. PMID 8247130. 
  4. ^ Freymann, D.M., Keenan, R.J., Stroud, R.M. and Walter, P. (1997). „Structure of the conserved GTPase domain of the signal recognition particle”. Nature. 385: 361—364. PMID 9002524. 

Literatura

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