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PMC	članci
PubMed	članci
NCBI	proteini

Vinorin hidroksilaza
Vinorin hidroksilaza
Identifikatori
EC broj	1.14.13.75
CAS broj	162875-03-8
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Vinorin hidroksilaza (EC 1.14.13.75, vinorinska hidroksilaza) je enzim sa sistematskim imenom vinorin,NADPH:kiseonik oksidoreduktaza (21alfa-hidroksilacija).^[1] Ovaj enzim katalizuje sledeću hemijsku reakciju

vinorin + NADPH + H⁺ + O₂

\rightleftharpoons

vomilenin + NADP⁺ + H₂O

Ovaj enzim je hem-tiolatni protein (P-450). On učestvuje u biosintezi indolnog alkaloida ajmalina.

Reference

^ Falkenhagen, H. & Stöckligt, J. (1995). „Enzymatic biosynthesis of vomilenine, a key intermediate of the ajmaline pathway, catalysed by a novel cytochrome P-450-dependent enzyme from plant cell cultures of Rauwolfia serpentina”. Z. Naturforsch. C: Biosci. 50: 45—53.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze

Vinorine+hydroxylase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Falkenhagen, H. & Stöckligt, J. (1995). „Enzymatic biosynthesis of vomilenine, a key intermediate of the ajmaline pathway, catalysed by a novel cytochrome P-450-dependent enzyme from plant cell cultures of Rauwolfia serpentina”. Z. Naturforsch. C: Biosci. 50: 45—53.

[1]