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Undekaprenil-difosfooligosaharid—protein glikotransferaza
Undekaprenil-difosfooligosaharid—protein glikotransferaza
Identifikatori
EC broj	2.4.99.19
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
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PMC	članci
PubMed	članci
NCBI	proteini

Undekaprenil-difosfooligosaharid—protein glikotransferaza (EC 2.4.99.19, PglB) je enzim sa sistematskim imenom tritrans,heptacis-undekaprenil-difosfooligosaharid:protein-L-asparagin N-beta-D-oligosaharidotransferaza.^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

tritrans,heptacis-undekaprenil difosfooligosaharid + [protein]-L-asparagin

\rightleftharpoons

tritrans,heptacis-undekaprenil difosfat + glikoprotein sa oligosaharidnim lancom vezanim N-beta-D-glikozilnom vezom za protein L-asparagin

Ovaj bakterijski enzim je izolovan iz Campylobacter jejuni i Campylobacter lari.

Reference

^ Maita, N., Nyirenda, J., Igura, M., Kamishikiryo, J. and Kohda, D. (2010). „Comparative structural biology of eubacterial and archaeal oligosaccharyltransferases”. J. Biol. Chem. 285: 4941—4950. PMID 20007322.
^ Lizak, C., Gerber, S., Numao, S., Aebi, M. and Locher, K.P. (2011). „X-ray structure of a bacterial oligosaccharyltransferase”. Nature. 474: 350—355. PMID 21677752.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

Undecaprenyl-diphosphooligosaccharide---protein+glycotransferase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Maita, N., Nyirenda, J., Igura, M., Kamishikiryo, J. and Kohda, D. (2010). „Comparative structural biology of eubacterial and archaeal oligosaccharyltransferases”. J. Biol. Chem. 285: 4941—4950. PMID 20007322.

[2] Lizak, C., Gerber, S., Numao, S., Aebi, M. and Locher, K.P. (2011). „X-ray structure of a bacterial oligosaccharyltransferase”. Nature. 474: 350—355. PMID 21677752.

[1]

[2]