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Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Tirukaladienolna sintaza
Tirukaladienolna sintaza
Identifikatori
EC broj	5.4.99.56
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Tirukaladienolna sintaza (EC 5.4.99.56, PEN3) je enzim sa sistematskim imenom (3S)-2,3-epoksi-2,3-dihidroskvalen mutaza (ciklizacija, formira tirukala-7,24-dien-3beta-ol).^[1] Ovaj enzim katalizuje sledeću hemijsku reakciju

(3S)-2,3-epoksi-2,3-dihidroskvalen

\rightleftharpoons

tirukala-7,24-dien-3beta-ol

Produkt enzima iz Arabidopsis thaliana je 85% tirukala-7,24-dien-3beta-ol sa tragovima drugih triterpenoida.

Reference

^ Morlacchi, P., Wilson, W.K., Xiong, Q., Bhaduri, A., Sttivend, D., Kolesnikova, M.D. and Matsuda, S.P. (2009). „Product profile of PEN3: the last unexamined oxidosqualene cyclase in Arabidopsis thaliana”. Org. Lett. 11: 2627—2630. PMID 19445469.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

Tirucalladienol+synthase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Morlacchi, P., Wilson, W.K., Xiong, Q., Bhaduri, A., Sttivend, D., Kolesnikova, M.D. and Matsuda, S.P. (2009). „Product profile of PEN3: the last unexamined oxidosqualene cyclase in Arabidopsis thaliana”. Org. Lett. 11: 2627—2630. PMID 19445469.

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