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PubMed	članci
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Tetrahidroberberin oksidaza
Tetrahidroberberin oksidaza
Identifikatori
EC broj	1.3.3.8
CAS broj	114705-00-9
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
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PMC	članci
PubMed	članci
NCBI	proteini

Tetrahidroberberin oksidaza (EC 1.3.3.8, (S)-THB oksidaza) je enzim sa sistematskim imenom (S)-tetrahidroberberin:kiseonik oksidoreduktaza.^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

(S)-tetrahidroberberin + 2 O₂

\rightleftharpoons

berberin + 2H₂O₂

Enzim iz Berberis sp. je flavoprotein, dok enzim iz Coptis japonica nije. (R)-tetrahidroberberini nisu supstrat ovog enzima.

Reference

^ Amann, M., Nagakura, N. and Zenk, M.H. (1984). „(S)-Tetrahydroprotoberberine oxidase the final enzyme in protoberberine biosynthesis”. Tetrahedron Lett. 25: 953—954.
^ Okada, N., Shinmyo, A., Okada, H. and Yamada, Y. (1988). „Purification and characterization of (S)-tetrahydroberberine oxidase from cultured Coptis japonica cells”. Phytochemistry. 27: 979—982.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

Tetrahydroberberine+oxidase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Amann, M., Nagakura, N. and Zenk, M.H. (1984). „(S)-Tetrahydroprotoberberine oxidase the final enzyme in protoberberine biosynthesis”. Tetrahedron Lett. 25: 953—954.

[2] Okada, N., Shinmyo, A., Okada, H. and Yamada, Y. (1988). „Purification and characterization of (S)-tetrahydroberberine oxidase from cultured Coptis japonica cells”. Phytochemistry. 27: 979—982.

[1]

[2]