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PubMed	članci
NCBI	proteini

TRNK pseudouridinska^38/39 sintaza
TRNK pseudouridinska38/39 sintaza
Identifikatori
EC broj	5.4.99.45
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
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NCBI	proteini

TRNK pseudouridinska^38/39 sintaza (EC 5.4.99.45, Deg1, Pus3p, pseudouridin sintaza 3) je enzim sa sistematskim imenom tRNK-uridin^38/39 uracil mutaza.^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

tRNK uridin^38/39

\rightleftharpoons

tRNK pseudouridin^38/39

Enzim iz Saccharomyces cerevisiae je aktivan samo na uridinu³⁸ i uridinu³⁹.

Reference

^ Lecointe, F., Simos, G., Sauer, A., Hurt, E.C., Motorin, Y. and Grosjean, H. (1998). „Characterization of yeast protein Deg1 as pseudouridine synthase (Pus3) catalyzing the formation of Ψ³⁸ and Ψ³⁹ in tRNA anticodon loop”. J. Biol. Chem. 273: 1316—1323. PMID 9430663.
^ Chen, J. & Patton, J.R. (2000). „Pseudouridine synthase 3 from mouse modifies the anticodon loop of tRNA”. Biochemistry. 39: 12723—12730. PMID 11027153.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

TRNA+pseudouridine38/39+synthase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Lecointe, F., Simos, G., Sauer, A., Hurt, E.C., Motorin, Y. and Grosjean, H. (1998). „Characterization of yeast protein Deg1 as pseudouridine synthase (Pus3) catalyzing the formation of Ψ³⁸ and Ψ³⁹ in tRNA anticodon loop”. J. Biol. Chem. 273: 1316—1323. PMID 9430663.

[2] Chen, J. & Patton, J.R. (2000). „Pseudouridine synthase 3 from mouse modifies the anticodon loop of tRNA”. Biochemistry. 39: 12723—12730. PMID 11027153.

[1]

[2]

TRNK pseudouridinska38/39 sintaza

Reference

Literatura

Spoljašnje veze