Sumpor nosilac protein ThiS adenililtransferaza
Sumpor nosilac protein ThiS adenililtransferaza (EC 2.7.7.73, thiF (gen)) je enzim sa sistematskim imenom ATP:(ThiS) adenililtransferaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- ATP + [ThiS] difosfat + adenilil-[ThiS]
Ovaj enzim vezuje jon Zn2+.
Reference
- ^ Taylor, S.V., Kelleher, N.L., Kinsland, C., Chiu, H.J., Costello, C.A., Backstrom, A.D., McLafferty, F.W. and Begley, T.P. (1998). „Thiamin biosynthesis in Escherichia coli. Identification of this thiocarboxylate as the immediate sulfur donor in the thiazole formation”. J. Biol. Chem. 273: 16555—16560. PMID 9632726.
- ^ Xi, J., Ge, Y., Kinsland, C., McLafferty, F.W. and Begley, T.P. (2001). „Biosynthesis of the thiazole moiety of thiamin in Escherichia coli: identification of an acyldisulfide-linked protein--protein conjugate that is functionally analogous to the ubiquitin/E1 complex”. Proc. Natl. Acad. Sci. USA. 98: 8513—8518. PMID 11438688.
- ^ Duda, D.M., Walden, H., Sfondouris, J. and Schulman, B.A. (2005). „Structural analysis of Escherichia coli ThiF”. J. Mol. Biol. 349: 774—786. PMID 15896804.
- ^ Lehmann, C., Begley, T.P. and Ealick, S.E. (2006). „Structure of the Escherichia coli ThiS-ThiF complex, a key component of the sulfur transfer system in thiamin biosynthesis”. Biochemistry. 45: 11—19. PMID 16388576.
Literatura
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