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Serin—piruvat transaminaza
Serin—piruvat transaminaza
Identifikatori
EC broj	2.6.1.51
CAS broj	9030-88-0
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
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PMC	članci
PubMed	članci
NCBI	proteini

Serin—piruvat transaminaza (EC 2.6.1.51, SPT, hidroksipiruvat:L-alanin transaminaza) je enzim sa sistematskim imenom L-serin:piruvat aminotransferaza.^[1]^[2]^[3] Ovaj enzim katalizuje sledeću hemijsku reakciju

L-serin + piruvat

\rightleftharpoons

3-hidroksipiruvat + L-alanin

Ovaj enzim je piridoksal-fosfatni protein. Jetreni enzim može da bude identičan sa EC 2.6.1.44 alanin-glioksilat transaminazom.

Reference

^ Cheung, G.P., Rosenblum, I. and Sallach, H.J. (1968). „Comparative studies of enzymes related to serine metabolism in higher plants”. Plant Physiol. 43: 1813—1820. PMID 5699148.
^ Kretovich, V.L. & Stepanovich, K.M. (1961). „[The synthesis of serine from hydroxypyruvate in plants.]”. Dokl. Akad. Nauk S.S.S.R. 139: 488—490.
^ Sallach, H.J. (1956). „Formation of serine from hydroxypyruvate and L-alanine”. J. Biol. Chem. 223: 1101—1108. PMID 13385257.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze

Serine---pyruvate+transaminase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Cheung, G.P., Rosenblum, I. and Sallach, H.J. (1968). „Comparative studies of enzymes related to serine metabolism in higher plants”. Plant Physiol. 43: 1813—1820. PMID 5699148.

[2] Kretovich, V.L. & Stepanovich, K.M. (1961). „[The synthesis of serine from hydroxypyruvate in plants.]”. Dokl. Akad. Nauk S.S.S.R. 139: 488—490.

[3] Sallach, H.J. (1956). „Formation of serine from hydroxypyruvate and L-alanine”. J. Biol. Chem. 223: 1101—1108. PMID 13385257.

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