RHC80267

RHC80267
Nazivi
IUPAC naziv
(cikloheksilideneamino)N-[6-[(cikloheksilidenamino)oksikarbonilamino]heksil]karbamat
Drugi nazivi
RHC 80267, RG 80267, U 57908
Identifikacija
3D model (Jmol)
ChemSpider
MeSH 1,6-bis(cyclohexyloximinocarbonyl)hexane
  • C1CCC(=NOC(=O)NCCCCCCNC(=O)ON=C2CCCCC2)CC1
Svojstva
C20H34N4O4
Molarna masa 394,26
Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa).
ДаY verifikuj (šta je ДаYНеН ?)
Reference infokutije

RHC80267 je inhibitor diacilglicerol lipaze[3]. Diacilglicerol lipaza generiše endokanabinoid 2-arahidonoilglicerol iz diacilglicerola.

Reference

  1. ^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.  уреди
  2. ^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1. 
  3. ^ Sutherland CA, Amin D (1982). „Relative activities of rat and dog platelet phospholipase A2 and diglyceride lipase. Selective inhibition of diglyceride lipase by RHC 80267”. J. Biol. Chem. 257 (23): 14006—10. PMID 7142192. 

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