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Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Protein ksiloziltransferaza
Protein ksiloziltransferaza
Identifikatori
EC broj	2.4.2.26
CAS broj	55576-38-0
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Protein ksiloziltransferaza (EC 2.4.2.26, UDP-D-ksiloza:protein osnove beta-D-ksiloziltransferaze, UDP-D-ksiloza:protein osnove ksiloziltransferaze, UDP-D-ksiloza:proteoglikan proteina osnove beta-D-ksiloziltransferaze, UDP-ksiloza-protein osnove beta-D-ksiloziltransferaze, uridin difosfoksiloza-protein osnove beta-ksiloziltransferaze, uridin difosfoksiloza-protein ksiloziltransferaza) je enzim sa sistematskim imenom UDP-D-ksiloza:protein beta-D-ksiloziltransferaza.^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

Prenosi beta-D-ksilozilni ostatak sa UDP-D-ksiloze na serinsku hidroksi grupu akceptora proteinskog supstrata

Ovaj enzim učestvuje u biosintezi vezivnog regiona glikozaminoglikanskih lanaca tokom biosinteze proteoglikana (hondroitina, dermatana i heparan sulfata).

Reference

^ Stoolmiller, A.C., Horwitz, A.L. and Dorfman, A. (1972). „Biosynthesis of the chondroitin sulfate proteoglycan. Purification and properties of xylosyltransferase”. J. Biol. Chem. 247: 3525—3532. PMID 5030630.
^ Götting, C., Kuhn, J., Zahn, R., Brinkmann, T. and Kleesiek, K. (2000). „Molecular cloning and expression of human UDP-D-xylose:proteoglycan core protein β-D-xylosyltransferase and its first isoform XT-II”. J. Mol. Biol. 304: 517—528. PMID 11099377.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

Protein+xylosyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Stoolmiller, A.C., Horwitz, A.L. and Dorfman, A. (1972). „Biosynthesis of the chondroitin sulfate proteoglycan. Purification and properties of xylosyltransferase”. J. Biol. Chem. 247: 3525—3532. PMID 5030630.

[2] Götting, C., Kuhn, J., Zahn, R., Brinkmann, T. and Kleesiek, K. (2000). „Molecular cloning and expression of human UDP-D-xylose:proteoglycan core protein β-D-xylosyltransferase and its first isoform XT-II”. J. Mol. Biol. 304: 517—528. PMID 11099377.

[1]

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