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Protein N-acetilglukozaminiltransferaza
Protein N-acetilglukozaminiltransferaza
Identifikatori
EC broj	2.4.1.94
CAS broj	72319-34-7
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Protein N-acetilglukozaminiltransferaza (EC 2.4.1.94, uridin difosfoacetilglukozamin-protein acetilglukozaminiltransferaza, uridin difosfo-N-acetilglukozamin:polipeptid beta-N-acetilglukozaminiltransferaza, N-acetilglukozaminiltransferaza I) je enzim sa sistematskim imenom UDP-N-acetil-D-glukozamin:(protein)-L-asparagin beta-N-acetil-D-glukozaminil-transferaza.^[1]^[2]^[3] Ovaj enzim katalizuje sledeću hemijsku reakciju

UDP-N-acetil-D-glukozamin + [protein]-L-asparagin

\rightleftharpoons

UDP + [protein]-N⁴-(N-acetil-D-glukozaminil)-L-asparagin

Akceptor je asparaginski ostatak u sequenci oblika Asn-Xaa-Thr or Asn-Xaa-Ser.

Reference

^ Khalkhali, Z. & Marshall, R.D. (1975). „Glycosylation of ribonuclease A catalysed by rabbit liver extracts”. Biochem. J. 146: 299—307. PMID 1156375.
^ Khalkhali, Z. & Marshall, R.D. (1976). „UDP-N-acetyl-D-glucosamine-asparagine sequon N-acetyl-β-D-glucosaminyl-transferase-activity in human serum”. Carbohydr. Res. 49: 455—473. PMID 986874.
^ Khalkhali, Z., Marshall, R.D., Reuvers, F., Habets-Willems, C. and Boer, P. (1976). „Glycosylation in vitro of an asparagine sequon catalysed by preparations of yeast cell membranes”. Biochem. J. 160: 37—41. PMID 795426.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze

Protein+N-acetylglucosaminyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Khalkhali, Z. & Marshall, R.D. (1975). „Glycosylation of ribonuclease A catalysed by rabbit liver extracts”. Biochem. J. 146: 299—307. PMID 1156375.

[2] Khalkhali, Z. & Marshall, R.D. (1976). „UDP-N-acetyl-D-glucosamine-asparagine sequon N-acetyl-β-D-glucosaminyl-transferase-activity in human serum”. Carbohydr. Res. 49: 455—473. PMID 986874.

[3] Khalkhali, Z., Marshall, R.D., Reuvers, F., Habets-Willems, C. and Boer, P. (1976). „Glycosylation in vitro of an asparagine sequon catalysed by preparations of yeast cell membranes”. Biochem. J. 160: 37—41. PMID 795426.

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