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Prolilna aminopeptidaza
Prolilna aminopeptidaza
Identifikatori
EC broj	3.4.11.5
CAS broj	9025-40-5
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
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PMC	članci
PubMed	članci
NCBI	proteini

Prolilna aminopeptidaza (EC 3.4.11.5, prolinska aminopeptidaza, Pro-X aminopeptidaza, citosolna aminopeptidaza V, prolinska iminopeptidaza) je enzim.^[1]^[2]^[3] Ovaj enzim katalizuje sledeću hemijsku reakciju

Odvajanje N-terminalnog prolina sa peptid

Za dejstvo ovog enzima je neophodan jon Mn²⁺.

Reference

^ Sarid, S., Berger, A. and Katchalski, E. (1962). „Proline iminopeptidase. II. Purification and comparison with iminopeptidase (prolinase)”. J. Biol. Chem. 237: 2207—2212. PMID 14497218.
^ Nordwig, A. & Mayer, H. (1973). „The cleavage of prolyl peptidases by kidney peptidases”. Hoppe-Seyler's Z. Physiol. Chem. 354: 380—383. PMID 4803482.
^ Turzynski, A. & Mentlein, R. (1990). „Prolyl aminopeptidase from rat brain and kidney. Action on peptides and identification as leucyl aminopeptidase”. Eur. J. Biochem. 190: 509—515. PMID 2373079.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze

Prolyl+aminopeptidase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Sarid, S., Berger, A. and Katchalski, E. (1962). „Proline iminopeptidase. II. Purification and comparison with iminopeptidase (prolinase)”. J. Biol. Chem. 237: 2207—2212. PMID 14497218.

[2] Nordwig, A. & Mayer, H. (1973). „The cleavage of prolyl peptidases by kidney peptidases”. Hoppe-Seyler's Z. Physiol. Chem. 354: 380—383. PMID 4803482.

[3] Turzynski, A. & Mentlein, R. (1990). „Prolyl aminopeptidase from rat brain and kidney. Action on peptides and identification as leucyl aminopeptidase”. Eur. J. Biochem. 190: 509—515. PMID 2373079.

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