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Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Neamin transaminaza
Neamin transaminaza
Identifikatori
EC broj	2.6.1.93
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Neamin transaminaza (EC 2.6.1.93, glutamat---6'-dehidroparomamin aminotransferaza, btrB (gen), neoN (gen), kacL (gen)) je enzim sa sistematskim imenom neamin:2-oksoglutarat aminotransferaza.^[1]^[2]^[3] Ovaj enzim katalizuje sledeću hemijsku reakciju

neamin + 2-oksoglutarat

\rightleftharpoons

6'-dehidroparomamin + L-glutamat

Ova reakcija se odvija u reverznom smeru.

Reference

^ Huang, F., Spiteller, D., Koorbanally, N.A., Li, Y., Llewellyn, N.M. and Spencer, J.B. (2007). „Elaboration of neosamine rings in the biosynthesis of neomycin and butirosin”. ChemBioChem. 8: 283—288. PMID 17206729.
^ Clausnitzer, D., Piepersberg, W. and Wehmeier, U.F. (2011). „The oxidoreductases LivQ and NeoQ are responsible for the different 6′-modifications in the aminoglycosides lividomycin and neomycin”. J. Appl. Microbiol. 111: 642—651. PMID 21689223.
^ Park, J.W., Park, S.R., Nepal, K.K., Han, A.R., Ban, Y.H., Yoo, Y.J., Kim, E.J., Kim, E.M., Kim, D., Sohng, J.K. and Yoon, Y.J. (2011). „Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation”. Nat. Chem. Biol. 7: 843—852. PMID 21983602.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze

Neamine+transaminase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Huang, F., Spiteller, D., Koorbanally, N.A., Li, Y., Llewellyn, N.M. and Spencer, J.B. (2007). „Elaboration of neosamine rings in the biosynthesis of neomycin and butirosin”. ChemBioChem. 8: 283—288. PMID 17206729.

[2] Clausnitzer, D., Piepersberg, W. and Wehmeier, U.F. (2011). „The oxidoreductases LivQ and NeoQ are responsible for the different 6′-modifications in the aminoglycosides lividomycin and neomycin”. J. Appl. Microbiol. 111: 642—651. PMID 21689223.

[3] Park, J.W., Park, S.R., Nepal, K.K., Han, A.R., Ban, Y.H., Yoo, Y.J., Kim, E.J., Kim, E.M., Kim, D., Sohng, J.K. and Yoon, Y.J. (2011). „Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation”. Nat. Chem. Biol. 7: 843—852. PMID 21983602.

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