PROFILPELAJAR.COM

Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

N-karbamoil-D-aminokiselinska hidrolaza
N-karbamoil-D-aminokiselinska hidrolaza
Identifikatori
EC broj	3.5.1.77
CAS broj	71768-08-6
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

N-karbamoil-D-aminokiselinska hidrolaza (EC 3.5.1.77, D-N-karbamoilaza, N-karbamoilaza) je enzim sa sistematskim imenom N-karbamoil-D-aminokiselina amidohidrolaza.^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

N-karbamoil-D-aminokiselina + H₂O

\rightleftharpoons

D-aminokiselina + NH₃ + CO₂

Ovaj enzim, zajedno sa EC 3.5.1.87 (N-karbamoil-L-aminokiselinskom hidrolazom), EC 5.1.99.5 (hidantoinskom racemazom) i hidantoinazom, formora deo reakcione kaskade poznate kao hidantoinazni proces.

Reference

^ Ogawa, J., Shimizu, S., Yamada, H. (1993). „N-Carbamoyl-D-amino acid amidohydrolase from Comamonas sp. E222c; purification and characterization”. Eur. J. Biochem. 212: 685—691. PMID 8462543.
^ Altenbuchner, J., Siemann-Herzberg, M. and Syldatk, C. (2001). „Hydantoinases and related enzymes as biocatalysts for the synthesis of unnatural chiral amino acids”. Curr. Opin. Biotechnol. 12: 559—563. PMID 11849938.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze

N-carbamoyl-D-amino-acid+hydrolase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Ogawa, J., Shimizu, S., Yamada, H. (1993). „N-Carbamoyl-D-amino acid amidohydrolase from Comamonas sp. E222c; purification and characterization”. Eur. J. Biochem. 212: 685—691. PMID 8462543.

[2] Altenbuchner, J., Siemann-Herzberg, M. and Syldatk, C. (2001). „Hydantoinases and related enzymes as biocatalysts for the synthesis of unnatural chiral amino acids”. Curr. Opin. Biotechnol. 12: 559—563. PMID 11849938.

[1]

[2]