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PMC	članci
PubMed	članci
NCBI	proteini

L-triptofan—piruvat aminotransferaza
L-triptofan—piruvat aminotransferaza
Identifikatori
EC broj	2.6.1.99
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

L-triptofan—piruvat aminotransferaza (EC 2.6.1.99, TAA1 (gen), vt2 (gen)) je enzim sa sistematskim imenom L-triptofan:piruvat aminotransferaza.^[1]^[2]^[3]^[4] Ovaj enzim katalizuje sledeću hemijsku reakciju

L-triptofan + piruvat

\rightleftharpoons

indol-3-piruvat + L-alanin

Ovaj biljni enzim, zajedno sa EC 1.14.13.168, indol-3-piruvat monooksigenazom, je je odgovoran za biosintezu biljnog hormona indol-3-acetata iz L-triptofana.

Reference

^ Tao, Y., Ferrer, J.L., Ljung, K., Pojer, F., Hong, F., Long, J.A., Li, L., Moreno, J.E., Bowman, M.E., Ivans, L.J., Cheng, Y., Lim, J., Zhao, Y., Ballare, C.L., Sandberg, G., Noel, J.P. and Chory, J. (2008). „Rapid synthesis of auxin via a new tryptophan-dependent pathway is required for shade avoidance in plants”. Cell. 133: 164—176. PMID 18394996.
^ Mashiguchi, K., Tanaka, K., Sakai, T., Sugawara, S., Kawaide, H., Natsume, M., Hanada, A., Yaeno, T., Shirasu, K., Yao, H., McSteen, P., Zhao, Y., Hayashi, K., Kamiya, Y. and Kasahara, H. (2011). „The main auxin biosynthesis pathway in Arabidopsis”. Proc. Natl. Acad. Sci. USA. 108: 18512—18517. PMID 22025724.
^ Phillips, K.A., Skirpan, A.L., Liu, X., Christensen, A., Slewinski, T.L., Hudson, C., Barazesh, S., Cohen, J.D., Malcomber, S. and McSteen, P. (2011). „vanishing tassel2 encodes a grass-specific tryptophan aminotransferase required for vegetative and reproductive development in maize”. Plant Cell. 23: 550—566. PMID 21335375.
^ Zhao, Y. (2012). „Auxin biosynthesis: a simple two-step pathway converts tryptophan to indole-3-acetic acid in plants”. Mol. Plant. 5: 334—338. PMID 22155950.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

L-tryptophan---pyruvate+aminotransferase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Tao, Y., Ferrer, J.L., Ljung, K., Pojer, F., Hong, F., Long, J.A., Li, L., Moreno, J.E., Bowman, M.E., Ivans, L.J., Cheng, Y., Lim, J., Zhao, Y., Ballare, C.L., Sandberg, G., Noel, J.P. and Chory, J. (2008). „Rapid synthesis of auxin via a new tryptophan-dependent pathway is required for shade avoidance in plants”. Cell. 133: 164—176. PMID 18394996.

[2] Mashiguchi, K., Tanaka, K., Sakai, T., Sugawara, S., Kawaide, H., Natsume, M., Hanada, A., Yaeno, T., Shirasu, K., Yao, H., McSteen, P., Zhao, Y., Hayashi, K., Kamiya, Y. and Kasahara, H. (2011). „The main auxin biosynthesis pathway in Arabidopsis”. Proc. Natl. Acad. Sci. USA. 108: 18512—18517. PMID 22025724.

[3] Phillips, K.A., Skirpan, A.L., Liu, X., Christensen, A., Slewinski, T.L., Hudson, C., Barazesh, S., Cohen, J.D., Malcomber, S. and McSteen, P. (2011). „vanishing tassel2 encodes a grass-specific tryptophan aminotransferase required for vegetative and reproductive development in maize”. Plant Cell. 23: 550—566. PMID 21335375.

[4] Zhao, Y. (2012). „Auxin biosynthesis: a simple two-step pathway converts tryptophan to indole-3-acetic acid in plants”. Mol. Plant. 5: 334—338. PMID 22155950.

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