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Izopentenil-difosfatna D-izomeraza
Izopentenil-difosfatna D-izomeraza
Identifikatori
EC broj	5.3.3.2
CAS broj	9033-27-6
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
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NCBI	proteini

Izopentenil-difosfatna D-izomeraza (EC 5.3.3.2, izopentenilpirofosfatna Delta-izomeraza, metilbutenilpirofosfatna izomeraza, izopentenilpirofosfatna izomeraza) je enzim sa sistematskim imenom izopentenil-difosfat Delta3-Delta2-izomeraza.^[1]^[2]^[3] Ovaj enzim katalizuje sledeću hemijsku reakciju

izopentenil difosfat

\rightleftharpoons

dimetilalil difosfat

Za dejstvo enzima iz Streptomyces sp. vrste CL190 su neophodni FMN i NAD(P)H kofaktori.

Reference

^ Kaneda, K., Kuzuyama, T., Takagi, M., Hayakawa, Y. and Seto, H. (2001). „An unusual isopentenyl diphosphate isomerase found in the mevalonate pathway gene cluster from Streptomyces sp. strain CL190”. Proc. Natl. Acad. Sci. USA. 98: 932—937. PMID 11158573.
^ Bishop, J.M. (1983). „Cellular oncogenes and retroviruses”. Annu. Rev. Biochem. 52: 301—354. PMID 6351725.
^ Agranoff, B.W., Eggerer, H., Henning, U. and Lynen, F. (1960). „Biosynthesis of terpenes. VII. Isopentenyl pyrophosphate isomerase”. J. Biol. Chem. 235: 326—332. PMID 13792054.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

Isopentenyl-diphosphate+Delta-isomerase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Kaneda, K., Kuzuyama, T., Takagi, M., Hayakawa, Y. and Seto, H. (2001). „An unusual isopentenyl diphosphate isomerase found in the mevalonate pathway gene cluster from Streptomyces sp. strain CL190”. Proc. Natl. Acad. Sci. USA. 98: 932—937. PMID 11158573.

[2] Bishop, J.M. (1983). „Cellular oncogenes and retroviruses”. Annu. Rev. Biochem. 52: 301—354. PMID 6351725.

[3] Agranoff, B.W., Eggerer, H., Henning, U. and Lynen, F. (1960). „Biosynthesis of terpenes. VII. Isopentenyl pyrophosphate isomerase”. J. Biol. Chem. 235: 326—332. PMID 13792054.

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