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PubMed	članci
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Glutationilspermidinska amidaza
Glutationilspermidinska amidaza
Identifikatori
EC broj	3.5.1.78
CAS broj	171040-71-4
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
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PMC	članci
PubMed	članci
NCBI	proteini

Glutationilspermidinska amidaza (EC 3.5.1.78, glutationilspermidinska amidohidrolaza (formira spermidin)) je enzim sa sistematskim imenom gama-L-glutamil-L-cisteinil-glicin:spermidin amidaza.^[1] Ovaj enzim katalizuje sledeću hemijsku reakciju

glutationilspermidin + H₂O

\rightleftharpoons

glutation + spermidin

Enzim iz Escherichia coli je bifunkcionalan i takođe katalizuje glutationilspermidinsku sintazu.

Reference

^ Bollinger, J.M., Kwon, D.S., Huisman, G.W., Kolter, R., Walsh, C.T. (1995). „Glutathionylspermidine metabolism in E. coli. Purification, cloning, overproduction and characterization of a bifunctional glutathionylspermidine synthetase/amidase”. J. Biol. Chem. 270: 14031—14041. PMID 7775463.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

Glutathionylspermidine+amidase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Bollinger, J.M., Kwon, D.S., Huisman, G.W., Kolter, R., Walsh, C.T. (1995). „Glutathionylspermidine metabolism in E. coli. Purification, cloning, overproduction and characterization of a bifunctional glutathionylspermidine synthetase/amidase”. J. Biol. Chem. 270: 14031—14041. PMID 7775463.

[1]