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Gingipain K
Gingipain K (EC 3.4.22.47, Lys-gingipain, PrtP proteinaza) je enzim.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Endopeptidaza sa striktnom specifičnošću za for lizinske veze
Aktivnost ovog enzima stimuliše glicin.
Reference
- ^ Pike, R., McGraw, W., Potempa, J. and Travis, J. (1994). „Lysine- and arginine-specific proteinases from Porphyromonas gingivalis. Isolation, characterization, and evidence for the existence of complexes with hemagglutinins”. J. Biol. Chem. 269: 406—411. PMID 8276827.
- ^ Curtis, M.A., Aduse, O.J., Rangarajan, M., Gallagher, A., Sterne, J.A., Reid, C.R., Evans, H.E. and Samuelsson, B. (2002). „Attenuation of the virulence of Porphyromonas gingivalis by using a specific synthetic Kgp protease inhibitor 2”. Infect. Immun. 70: 6968—6975. PMID 12438376.
Literatura
Spoljašnje veze
- Gingipain+K на US National Library of Medicine Medical Subject Headings (MeSH)
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