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Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Geraniol 8-hidroksilaza
Geraniol 8-hidroksilaza
Identifikatori
EC broj	1.14.13.152
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Geraniol 8-hidroksilaza (EC 1.14.13.152, CYP76B6, G10H, CrG10H, SmG10H) je enzim sa sistematskim imenom geraniol,NADPH:kiseonik oksidoreduktaza (8-hidroksilacija).^[1]^[2]^[3] Ovaj enzim katalizuje sledeću hemijsku reakciju

geraniol + NADPH + H⁺ + O₂

\rightleftharpoons

(6E)-8-hidroksigeraniol + NADP⁺ + H₂O

Ovaj enzim koristi citohrom P-450. On takođe deluje na nerol i citronelol.

Reference

^ Collu, G., Unver, N., Peltenburg-Looman, A.M., van der Heijden, R., Verpoorte, R. and Memelink, J. (2001). „Geraniol 10-hydroxylase, a cytochrome P450 enzyme involved in terpenoid indole alkaloid biosynthesis”. FEBS Lett. 508: 215—220. PMID 11718718.
^ Wang, J., Liu, Y., Cai, Y., Zhang, F., Xia, G. and Xiang, F. (2010). „Cloning and functional analysis of geraniol 10-hydroxylase, a cytochrome P450 from Swertia mussotii Franch”. Biosci. Biotechnol. Biochem. 74: 1583—1590. PMID 20699579.
^ Sung, P.H., Huang, F.C., Do, Y.Y. and Huang, P.L. (2011). „Functional expression of geraniol 10-hydroxylase reveals its dual function in the biosynthesis of terpenoid and phenylpropanoid”. J. Agric. Food Chem. 59: 4637—4643. PMID 21504162.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

Geraniol+8-hydroxylase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Collu, G., Unver, N., Peltenburg-Looman, A.M., van der Heijden, R., Verpoorte, R. and Memelink, J. (2001). „Geraniol 10-hydroxylase, a cytochrome P450 enzyme involved in terpenoid indole alkaloid biosynthesis”. FEBS Lett. 508: 215—220. PMID 11718718.

[2] Wang, J., Liu, Y., Cai, Y., Zhang, F., Xia, G. and Xiang, F. (2010). „Cloning and functional analysis of geraniol 10-hydroxylase, a cytochrome P450 from Swertia mussotii Franch”. Biosci. Biotechnol. Biochem. 74: 1583—1590. PMID 20699579.

[3] Sung, P.H., Huang, F.C., Do, Y.Y. and Huang, P.L. (2011). „Functional expression of geraniol 10-hydroxylase reveals its dual function in the biosynthesis of terpenoid and phenylpropanoid”. J. Agric. Food Chem. 59: 4637—4643. PMID 21504162.

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