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Eksodezoksiribonukleaza III
Eksodezoksiribonukleaza III
Identifikatori
EC broj	3.1.11.2
CAS broj	9037-44-9
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Eksodezoksiribonukleaza III (EC 3.1.11.2, Escherichia coli eksonukleaza III, E. coli eksonukleaza III, endoribonukleaza III) je enzim sa sistematskim imenom '.^[1]^[2]^[3] Ovaj enzim katalizuje sledeću hemijsku reakciju

Eksonukleolitičko razlaganje u 3'- ka 5'- smeru čime se formiraju nukleozid 5'-fosfati

Ova enzim preferentno deluje na dvolačanu DNK.

Reference

^ Lindahl, T., Gally, J.A. and Edelman, G.M. (1969). „Properties of deoxyribonuclease 3 from mammalian tissues”. J. Biol. Chem. 244: 5014—5019. PMID 5824576.
^ Richardson, C.C. & Kornberg, A. (1964). „A deoxyribonucleic acid phosphatase-exonuclease from Escherichia coli. I. Purification of the enzyme and characterization of the phosphatase activity”. J. Biol. Chem. 239: 242—250. PMID 14114850.
^ Richardson, C.C., Lehman, I.R. and Kornberg, A. (1964). „A deoxyribonucleic acid phosphatase-exonuclease from Escherichia coli. II. Characterization of the exonuclease activity”. J. Biol. Chem. 239: 251—258. PMID 14114851.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze

Exodeoxyribonuclease+III на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Lindahl, T., Gally, J.A. and Edelman, G.M. (1969). „Properties of deoxyribonuclease 3 from mammalian tissues”. J. Biol. Chem. 244: 5014—5019. PMID 5824576.

[2] Richardson, C.C. & Kornberg, A. (1964). „A deoxyribonucleic acid phosphatase-exonuclease from Escherichia coli. I. Purification of the enzyme and characterization of the phosphatase activity”. J. Biol. Chem. 239: 242—250. PMID 14114850.

[3] Richardson, C.C., Lehman, I.R. and Kornberg, A. (1964). „A deoxyribonucleic acid phosphatase-exonuclease from Escherichia coli. II. Characterization of the exonuclease activity”. J. Biol. Chem. 239: 251—258. PMID 14114851.

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