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PMC	članci
PubMed	članci
NCBI	proteini

Dugolančana-masna-acil-KoA reduktaza
Dugolančana-masna-acil-KoA reduktaza
Identifikatori
EC broj	1.2.1.50
CAS broj	50936-56-6
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Dugolančana-masna-acil-KoA reduktaza (EC 1.2.1.50, acil-KoA reduktaza, acil koenzim A reduktaza) je enzim sa sistematskim imenom dugolančani aldehid:NADP⁺ oksidoreduktaza (formira acil-KoA).^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

dugolančani aldehid + KoA + NADP⁺

\rightleftharpoons

dugolančani acil-KoA + NADPH + H⁺

Zajedno sa EC 6.2.1.19, ligazom dugolančane masne-kiseline---luciferin-komponente, formira reduktazni sistem masnih kiselina koji formura supstrat za EC 1.14.14.3, alkanalnu monooksigenazu (FMN-vezanu). Ona je deo bakterijskog luciferaznog sistema.

Reference

^ Riendeau, D., Rodrigues, A. and Meighen, E. (1982). „Resolution of the fatty acid reductase from Photobacterium phosphoreum into acyl protein synthetase and acyl-CoA reductase activities. Evidence for an enzyme complex”. J. Biol. Chem. 257: 6908—6915. PMID 7085612.
^ Wall, L. & Meighen, E.A. (1986). „Subunit structure of the fatty-acid reductase complex from Photobacterium phosphoreum”. Biochemistry. 25: 4315—4321.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze

Long-chain-fatty-acyl-CoA+reductase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Riendeau, D., Rodrigues, A. and Meighen, E. (1982). „Resolution of the fatty acid reductase from Photobacterium phosphoreum into acyl protein synthetase and acyl-CoA reductase activities. Evidence for an enzyme complex”. J. Biol. Chem. 257: 6908—6915. PMID 7085612.

[2] Wall, L. & Meighen, E.A. (1986). „Subunit structure of the fatty-acid reductase complex from Photobacterium phosphoreum”. Biochemistry. 25: 4315—4321.

[1]

[2]