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Dodecenoil-KoA D-izomeraza
Dodecenoil-KoA D-izomeraza
Identifikatori
EC broj	5.3.3.8
CAS broj	62213-29-0
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
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Dodecenoil-KoA D-izomeraza (EC 5.3.3.8, dodecenoil-KoA Delta-izomeraza, Delta3-cis-Delta2-trans-enoil-KoA izomeraza, acetilen-alenska izomeraza, dodecenoil-KoA Delta-izomeraza, dodecenoil-KoA Delta3-cis-Delta2-trans-izomeraza) je enzim sa sistematskim imenom dodecenoil-KoA (3Z)-(2E)-izomeraza.^[1]^[2]^[3]^[4] Ovaj enzim katalizuje sledeću hemijsku reakciju

(3Z)-dodec-3-enoil-KoA

\rightleftharpoons

(2E)-dodec-2-enoil-KoA

Ovaj enzim takođe katalizuje interkonverziju 3-acetilenskih masnih acil tioestara i (+)-2,3-dienoilnih masnih acil tioestara.

Reference

^ Miesowicz, F.M. & Bloch, K. (1979). „Purification of hog liver isomerase. Mechanism of isomerization of 3-alkenyl and 3-alkynyl thioesters”. J. Biol. Chem. 254: 5868—5877. PMID 376522.
^ Stoffel, W., Ditzer, R. and Caesar, H. (1964). „Der Stoffwechsel der ungesättigten Fettsäuren. III. Zur β-Oxydation der Mono- und Polyenfettsäuren. Der Mechanismus der enzymatischen Reaktionen an Δ³cis-Enoyl-CoA-Verbindungen”. Hoppe-Seyler's Z. Physiol. Chem. 339: 167—181. PMID 5830064.
^ Stoffel, W. & Ecker, W. (1979). „Δ³-cis,-Δ²-trans-Enoyl-CoA isomerase from rat liver mitochondria”. Methods Enzymol. 14: 99—105.
^ Stoffel, W. & Grol, M. (1978). „Purification and properties of 3-cis-2-trans-enoyl-CoA isomerase (dodecenoyl-CoA Δ-isomerase) from rat liver mitochondria”. Hoppe-Seyler's Z. Physiol. Chem. 359: 1777—1782. PMID 738702.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

Dodecenoyl-CoA+isomerase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Miesowicz, F.M. & Bloch, K. (1979). „Purification of hog liver isomerase. Mechanism of isomerization of 3-alkenyl and 3-alkynyl thioesters”. J. Biol. Chem. 254: 5868—5877. PMID 376522.

[2] Stoffel, W., Ditzer, R. and Caesar, H. (1964). „Der Stoffwechsel der ungesättigten Fettsäuren. III. Zur β-Oxydation der Mono- und Polyenfettsäuren. Der Mechanismus der enzymatischen Reaktionen an Δ³cis-Enoyl-CoA-Verbindungen”. Hoppe-Seyler's Z. Physiol. Chem. 339: 167—181. PMID 5830064.

[3] Stoffel, W. & Ecker, W. (1979). „Δ³-cis,-Δ²-trans-Enoyl-CoA isomerase from rat liver mitochondria”. Methods Enzymol. 14: 99—105.

[4] Stoffel, W. & Grol, M. (1978). „Purification and properties of 3-cis-2-trans-enoyl-CoA isomerase (dodecenoyl-CoA Δ-isomerase) from rat liver mitochondria”. Hoppe-Seyler's Z. Physiol. Chem. 359: 1777—1782. PMID 738702.

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