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Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Dezoksisarpagin hidroksilaza
Dezoksisarpagin hidroksilaza
Identifikatori
EC broj	1.14.13.91
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Dezoksisarpagin hidroksilaza (EC 1.14.13.91, DOSH) je enzim sa sistematskim imenom 10-dezoksisarpagin,NADPH:kiseonik oksidoreduktaza (10-hidroksilacija).^[1] Ovaj enzim katalizuje sledeću hemijsku reakciju

10-dezoksisarpagin + NADPH + H⁺ + O₂

\rightleftharpoons

sarpagin + NADP⁺ + H₂O

Ovaj enzim jehem-tiolatni protein (P-450).

Reference

^ Yu, B., Ruppert, M. and Stöckigt, J. (2002). „Deoxysarpagine hydroxylase — a novel enzyme closing a short side pathway of alkaloid biosynthesis in Rauvolfia”. Bioorg. Med. Chem. 10: 2479—2483. PMID 12057637.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

Deoxysarpagine+hydroxylase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Yu, B., Ruppert, M. and Stöckigt, J. (2002). „Deoxysarpagine hydroxylase — a novel enzyme closing a short side pathway of alkaloid biosynthesis in Rauvolfia”. Bioorg. Med. Chem. 10: 2479—2483. PMID 12057637.

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