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Ciklaza purinskog imidazolnog prstena
Ciklaza purinskog imidazolnog prstena
Identifikatori
EC broj	4.3.2.4
CAS broj	95990-28-6
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
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NCBI	proteini

Ciklaza purinskog imidazolnog prstena (EC 4.3.2.4, DNK-4,6-diamino-5-formamidopirimidin 8-C,9-N-lijaza (ciklizacija), DNK-4,6-diamino-5-formamidopirimidin 8-C,9-N-lijaza (ciklizacija, formira DNK-adenin)) je enzim sa sistematskim imenom DNK-4,6-diamino-5-formamidopirimidin C8-N9-lijaza (ciklizacija, formira DNK-adenin).^[1] Ovaj enzim katalizuje sledeću hemijsku reakciju

DNK 4,6-diamino-5-formamidopirimidin

\rightleftharpoons

DNK adenin + H₂O

Ovaj enzikm takođe deluje na 2,6-diamino-5-formamido-3,4-dihidro-4-oksopirimidinske ostatke.

Reference

^ Chetsanga, C.J. & Grigorian, C. (1985). „In situ enzymatic reclosure of opened imidazole rings of purines in DNA damaged by γ-irradiation”. Proc. Natl. Acad. Sci. USA. 82: 633—637. PMID 3856219.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze

Purine+imidazole-ring+cyclase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Chetsanga, C.J. & Grigorian, C. (1985). „In situ enzymatic reclosure of opened imidazole rings of purines in DNA damaged by γ-irradiation”. Proc. Natl. Acad. Sci. USA. 82: 633—637. PMID 3856219.

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