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Benzoat 1,2-dioksigenaza
Benzoat 1,2-dioksigenaza
Identifikatori
EC broj	1.14.12.10
CAS broj	9059-18-1
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
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Benzoat 1,2-dioksigenaza (EC 1.14.12.10, benzoatna hidroksilaza, benzoatna hidroksilaza, benzoinska hidroksilaza, benzoatna dioksigenaza) je enzim sa sistematskim imenom benzoat,NADH:kiseonik oksidoreduktaza (1,2-hidroksilacija).^[1]^[2]^[3] Ovaj enzim katalizuje sledeću hemijsku reakciju

benzoat + NADH + H⁺ + O₂

\rightleftharpoons

(1R,6S)-1,6-dihidroksicikloheksa-2,4-dien-1-karboksilat + NAD⁺

Ovaj enzim sadrži Fe²⁺.

Reference

^ Yamaguchi, M. & Fujisawa, H. (1978). „Characterization of NADH-cytochrome c reductase, a component of benzoate 1,2-dioxygenase system from Pseudomonas arvilla C-1”. J. Biol. Chem. 253: 8848—8853. PMID 214433.
^ Yamaguchi, M. & Fujisawa, H. (1980). „Purification and characterization of an oxygenase component in benzoate 1,2-dioxygenase system from Pseudomonas arvilla C-1”. J. Biol. Chem. 255: 5058—5063. PMID 7372624.
^ Yamaguchi, M. & Fujisawa, H. (1982). „Subunit structure of oxygenase component in benzoate-1,2-dioxygenase system from Pseudomonas arvilla C-1”. J. Biol. Chem. 257: 12497—12502. PMID 7130163.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

Benzoate+1,2-dioxygenase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Yamaguchi, M. & Fujisawa, H. (1978). „Characterization of NADH-cytochrome c reductase, a component of benzoate 1,2-dioxygenase system from Pseudomonas arvilla C-1”. J. Biol. Chem. 253: 8848—8853. PMID 214433.

[2] Yamaguchi, M. & Fujisawa, H. (1980). „Purification and characterization of an oxygenase component in benzoate 1,2-dioxygenase system from Pseudomonas arvilla C-1”. J. Biol. Chem. 255: 5058—5063. PMID 7372624.

[3] Yamaguchi, M. & Fujisawa, H. (1982). „Subunit structure of oxygenase component in benzoate-1,2-dioxygenase system from Pseudomonas arvilla C-1”. J. Biol. Chem. 257: 12497—12502. PMID 7130163.

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