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Aldehid reduktaza
Aldehid reduktaza
Identifikatori
EC broj	1.1.1.21
CAS broj	9028-31-3
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Aldehid reduktaza (EC 1.1.1.21, aldehidna reduktaza, aldoza reduktaza, poliol dehidrogenaza (NADP⁺), ALR2, alditol:NADP⁺ oksidoreduktaza, alditol:NADP⁺ 1-oksidoreduktaza, NADPH-aldopentoza reduktaza, NADPH-aldoza reduktaza) je enzim sa sistematskim imenom alditol:NAD(P)+ 1-oksidoreduktaza.^[1]^[2]^[3]^[4] Ovaj enzim katalizuje sledeću hemijsku reakciju

alditol + NAD(P)⁺

\rightleftharpoons

aldoza + NAD(P)H + H⁺

Ima široku specifičnost.

Reference

^ Attwood, M.A. & Doughty, C.C. (1974). „Purification and properties of calf liver aldose reductase”. Biochim. Biophys. Acta. 370: 358—368. PMID 4216364.
^ Boghosian, R.A. & McGuinness, E.T. (1979). „Affinity purification and properties of porcine brain aldose reductase”. Biochim. Biophys. Acta. 567: 278—286. PMID 36151.
^ Hers, H.G. (1960). „L’Aldose-réductase”. Biochim. Biophys. Acta. 37: 120—126. PMID 14401390.
^ Scher, B.M. & Horecker, B.L. (1966). „Pentose metabolism in Candida. 3. The triphosphopyridine nucleotide-specific polyol dehydrogenase of Candida utilis”. Arch. Biochem. Biophys. 116: 117—128. PMID 4381350.

Literatura

Ferrier, Denise R. (2005). Lippincott's Illustrated Reviews: Biochemistry (Lippincott's Illustrated Reviews). Hagerstown, Maryland: Lippincott Williams & Wilkins. стр. 319. ISBN 978-0-7817-2265-0.
Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze

Aldehyde+reductase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Attwood, M.A. & Doughty, C.C. (1974). „Purification and properties of calf liver aldose reductase”. Biochim. Biophys. Acta. 370: 358—368. PMID 4216364.

[2] Boghosian, R.A. & McGuinness, E.T. (1979). „Affinity purification and properties of porcine brain aldose reductase”. Biochim. Biophys. Acta. 567: 278—286. PMID 36151.

[3] Hers, H.G. (1960). „L’Aldose-réductase”. Biochim. Biophys. Acta. 37: 120—126. PMID 14401390.

[4] Scher, B.M. & Horecker, B.L. (1966). „Pentose metabolism in Candida. 3. The triphosphopyridine nucleotide-specific polyol dehydrogenase of Candida utilis”. Arch. Biochem. Biophys. 116: 117—128. PMID 4381350.

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