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PubMed	članci
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7-metilksantin demetilaza
7-metilksantin demetilaza
Identifikatori
EC broj	1.14.13.128
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

7-metilksantin demetilaza (EC 1.14.13.128, 7-metilksantinska demetilaza) je enzim sa sistematskim imenom 7-metilksantin:kiseonik oksidoreduktaza (demetilacija).^[1] Ovaj enzim katalizuje sledeću hemijsku reakciju:

7-metilksantin + O₂ + NAD(P)H + H⁺

\rightleftharpoons

ksantin + NAD(P)⁺ + H₂O + formaldehid

Ovaj enzim je oksigenaza u kojoj gvožđe nije vezano za hem. NADH je preferentni kofaktor.

Reference

^ Summers, R.M., Louie, T.M., Yu, C.L. and Subramanian, M. (2011). „Characterization of a broad-specificity non-haem iron N-demethylase from Pseudomonas putida CBB5 capable of utilizing several purine alkaloids as sole carbon and nitrogen source”. Microbiology. 157: 583—592. PMID 20966097.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

7-methylxanthine+demethylase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Summers, R.M., Louie, T.M., Yu, C.L. and Subramanian, M. (2011). „Characterization of a broad-specificity non-haem iron N-demethylase from Pseudomonas putida CBB5 capable of utilizing several purine alkaloids as sole carbon and nitrogen source”. Microbiology. 157: 583—592. PMID 20966097.

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