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3b-hidroksi-5a-steroid dehidrogenaza
3b-hidroksi-5a-steroid dehidrogenaza
Identifikatori
EC broj	1.1.1.278
CAS broj	58875-02-8
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
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3b-hidroksi-5a-steroid dehidrogenaza (EC 1.1.1.278, 3b-hidroksi-5a-steroidna dehidrogenaza) je enzim sa sistematskim imenom 3beta-hidroksi-5alfa-steroid:NADP⁺ 3-oksidoreduktaza.^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

3beta-hidroksi-5alfa-pregnan-20-on + NADP⁺

\rightleftharpoons

5alfa-pregnan-3,20-dion + NADPH + H⁺

Reference

^ Lindemann, P. & Luckner, M. (1997). „Biosynthesis of pregnane derivatives in somatic embryos of Digitalis lanata”. Phytochemistry. 46: 507—513.
^ Warneck, H.M. & Seitz, H.U. (1990). „3β-Hydroxysteroid oxidoreductase in suspension cultures of Digitalis lanata EHRH”. Z. Naturforsch. C: Biosci. 45: 963—972. PMID 2291772.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze

3beta-hydroxy-5alpha-steroid+dehydrogenase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Lindemann, P. & Luckner, M. (1997). „Biosynthesis of pregnane derivatives in somatic embryos of Digitalis lanata”. Phytochemistry. 46: 507—513.

[2] Warneck, H.M. & Seitz, H.U. (1990). „3β-Hydroxysteroid oxidoreductase in suspension cultures of Digitalis lanata EHRH”. Z. Naturforsch. C: Biosci. 45: 963—972. PMID 2291772.

[1]

[2]