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3-(imidazol-5-il)laktat dehidrogenaza
3-(imidazol-5-il)laktat dehidrogenaza
Identifikatori
EC broj	1.1.1.111
CAS broj	37250-42-3
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IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
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3-(imidazol-5-il)laktat dehidrogenaza (EC 1.1.1.111, imidazol-5-il laktat dehidrogenaza) je enzim sa sistematskim imenom (S)-3-(imidazol-5-il)laktat:NAD(P)⁺ oksidoreduktaza.^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

(S)-3-(imidazol-5-il)laktat + NAD(P)+

\rightleftharpoons

3-(imidazol-5-il)piruvat + NAD(P)H + H⁺

Reference

^ Coote, J.G. & Hassall, H. (1969). „The role of imidazol-5-yl-lactate-nicotinamide-adenine dinucleotide phosphate oxidoreductase and histidine-2-oxoglutarate aminotransferase in the degradation of imidazol-5-yl-lactate by Pseudomonas acidovorans”. Biochem. J. 111: 237—239. PMID 4303364.
^ Cortese, R., Brevet, J., Hedegaard, J. and Roche, J. (1968). „[Identification and purification of an α-ketoacid aromatic reductase of Escherichia coli B]”. C.R. Seances Soc. Biol. Fil. 162: 390—395. PMID 4237631.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze

3-(imidazol-5-yl)lactate+dehydrogenase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Coote, J.G. & Hassall, H. (1969). „The role of imidazol-5-yl-lactate-nicotinamide-adenine dinucleotide phosphate oxidoreductase and histidine-2-oxoglutarate aminotransferase in the degradation of imidazol-5-yl-lactate by Pseudomonas acidovorans”. Biochem. J. 111: 237—239. PMID 4303364.

[2] Cortese, R., Brevet, J., Hedegaard, J. and Roche, J. (1968). „[Identification and purification of an α-ketoacid aromatic reductase of Escherichia coli B]”. C.R. Seances Soc. Biol. Fil. 162: 390—395. PMID 4237631.

[1]

[2]